CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM20290
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor 4-(3-cyclopentyloxy-4-methoxyphenyl)-1-[[3-iodo-5-[3-(trifluoromethyl)diazirin-3-yl]phenyl]methyl]pyrrolidin-2-one family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00455265 Functional Category Bioactive
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4C and cAMP-specific 3',5'-cyclic phosphodiesterase 4B Binder Superfamily
Class Class 333

Cousin Family NamesSeedsMembers
Endothelin-1 receptor Ligand Atrasentan Family 127 336
Substance-P receptor Ligand DA-5018 Family 14 73
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 16
Kappa-type opioid receptor and Delta-type opioid receptor liga... 1 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor Sure... 4 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00455265 CHEMBL126587 Bioactive 4-(3-cyclopentyloxy-4-methoxyphenyl)-1-[[3-iodo-5-[3-(trifluoromethyl)diazirin-3-yl]phenyl]methyl]pyrrolidin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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