CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2031
Family Name Protein kinase C alpha type inhibitor 5-[3,5-bis(trifluoromethyl)phenyl]-N-[(2S,5S)-5-(hydroxymethyl)-1-methyl-3-oxo-2-propan-2-yl-2,4,5,6-tetrahydro-1,4-benzodiazocin-8-yl]pentanamide family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00329713 Functional Category Bioactive
Superfamily Protein kinase C eta type and Protein kinase C delta type Inhibitor 8-octyl-benzolactam-v9 Superfamily
Class Class 348

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Protein kinase C eta type and Protein kinase C delta type Inhi... 9 12
Sphingosine kinase 2 Inhibitor (r)-2-amino-4-hydroxy-n-(4-octy... 3 9
Protein kinase C delta type and Protein kinase C alpha type in... 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00329714 CHEMBL123244 Bioactive N-[(2S,5S)-5-(hydroxymethyl)-1-methyl-3-oxo-2-propan-2-yl-2,4,5,6-tetrahydro-1,4-benzodiazocin-8-yl]-5-[4-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)phenyl]pentanamide
CFAMM00329713 CHEMBL333323 Bioactive 5-[3,5-bis(trifluoromethyl)phenyl]-N-[(2S,5S)-5-(hydroxymethyl)-1-methyl-3-oxo-2-propan-2-yl-2,4,5,6-tetrahydro-1,4-benzodiazocin-8-yl]pentanamide
CFAMM00329715 CHEMBL330952 Bioactive (2E,4E)-5-[3,5-bis(trifluoromethyl)phenyl]-N-[(2S,5S)-5-(hydroxymethyl)-1-methyl-3-oxo-2-propan-2-yl-2,4,5,6-tetrahydro-1,4-benzodiazocin-8-yl]penta-2,4-dienamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27075 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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