CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM20353
Family Name Corticotropin-releasing factor receptor 1 ligand 3-[6-(dimethylamino)-4-methylpyridin-3-yl]-2,5-dimethyl-N-[1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00455480 Functional Category Bioactive
Superfamily Aurora kinase A and Aurora kinase B Binder Superfamily 5
Class Class 3234

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
HER Inhibitor AC480 Family 4 67
Tyrosine-protein kinase JAK2 Inhibitor INCB18424 Family 3 130
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 1 2
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 8 7
Adenosine receptor A3 and Adenosine receptor A1 ligand AGN-PC-... 5 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 34 11
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 46 9
Ephrin type-B receptor 4 ligand SureCN3289519 family 4 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 13 10
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 6 1
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Adenosine receptor A2a ligand AGN-PC-077RWY family 4 5
Prothrombin and Survival motor neuron protein inhibitor CHEMBL... 2 14
Survival motor neuron protein inhibitor CHEMBL1583999 family 1 3
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL1... 7 4
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 1
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 3
Vascular endothelial growth factor receptor 1 and Vascular end... 4 0
Casein kinase II subunit alpha and Homeodomain-interacting pro... 5 0
Casein kinase II subunit alpha inhibitor N-[5-[[3-cyano-7-(cyc... 3 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 1
Tyrosine-protein kinase JAK2 inhibitor N-[3-(3-chlorophenyl)-1... 12 4
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 6 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 26 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00455480 CHEMBL1288027 Bioactive 3-[6-(dimethylamino)-4-methylpyridin-3-yl]-2,5-dimethyl-N-[1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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