CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM20354
Family Name Glutamate carboxypeptidase 2 inhibitor 1-[(3-carboxyphenyl)methyl]-3-(2-sulfanylethyl)indole-2-carboxylic acid family
No. of Seeds 4 No. of Other Members 11
Family Centroid CFAMM00455486 Functional Category Bioactive
Superfamily SF1 Superfamily
Class Class 1261

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Ketorolac Family 3 40
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Retinoic acid receptor alpha Ligand LG100268 Family 2 33
SF1 family 1 10
Dihydroorotate dehydrogenase Inhibitor Cinchoninic Acid Family 1 21
AP endonuclease APE1 Inhibitor 5-fluoro-1h-indole-2-carboxylic... 2 61
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Fatty acid-binding protein, adipocyte Inhibitor 1-benzyl-2,3-d... 1 8
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
5-hydroxytryptamine receptor 3A Ligand 3alpha-(1'-methyl-2'-in... 2 17
Prostaglandin E2 receptor EP4 subtype and Prostaglandin D2 rec... 8 17
NS5B protein inhibitor AC1NQMYG family 6 12
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4R,... 3 7
Glutamate receptor ionotropic, NMDA 1 ligand (3S)-3-[2-[4-(ami... 2 2
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4S,... 5 2
Prostaglandin D2 receptor 2 ligand SureCN2189431 family 7 1
NS5B protein inhibitor AC1NQMYP family 5 0
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 4 4
C-C chemokine receptor type 2 ligand AGN-PC-03NT5I family 5 18
Glutamate receptor 4 and Glutamate receptor 2 ligand SureCN437... 4 12
Glutamate receptor 2 and Glutamate receptor 4 ligand SureCN828... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00455486 CHEMBL1288230 Bioactive 1-[(3-carboxyphenyl)methyl]-3-(2-sulfanylethyl)indole-2-carboxylic acid
CFAMM00455484 CHEMBL1288259 Bioactive AGN-PC-09M5XA
CFAMM00455483 CHEMBL1288286 Bioactive 1-[(3-tert-butyl-5-carboxyphenyl)methyl]-3-(2-sulfanylethyl)indole-2-carboxylic acid
CFAMM00455496 CHEMBL1288229 Bioactive 1-[(2-carboxyphenyl)methyl]-3-(2-sulfanylethyl)indole-2-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27254 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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