CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM20399
Family Name Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptamine receptor 1A ligand Tocris-1440 family
No. of Seeds 6 No. of Other Members 10
Family Centroid CFAMM00455642 Functional Category Bioactive
Superfamily Sigma non-opioid intracellular receptor 1 and D(2) dopamine receptor Binder Superfamily 2
Class Class 3379

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 4 30
Potassium voltage-gated channel subfamily H member 2 and Melan... 2 8
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 0
Glycogen synthase kinase-3 beta inhibitor AGN-PC-0802SH family 1 2
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 1 6
D(4) dopamine receptor ligand (1Z)-1-hydroxyimino-1-(3-methylp... 1 5
Beta-secretase 1 and Potassium voltage-gated channel subfamily... 3 4
Sigma non-opioid intracellular receptor 1 and Alpha-1B adrener... 2 1
Aromatase inhibitor AGN-PC-00O3GK family 1 1


External ID

Functional Category

Molecule Name

CFAMM00455637 CHEMBL139595 Bioactive AGN-PC-00EWQF
CFAMM00455643 CHEMBL140650 Bioactive SureCN9765995
CFAMM00455642 CHEMBL129768 Bioactive Tocris-1440
CFAMM00455634 CHEMBL60859 Bioactive Bmy-14802
CFAMM00455646 CHEMBL61177 Bioactive SureCN9766006
CFAMM00455631 CHEMBL141670 Bioactive 4-[4-(5-bromopyrimidin-2-yl)piperazin-1-yl]-1-(4-fluorophenyl)butan-1-ol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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