CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM204
Family Name Pol polyprotein and Protease inhibitor 161186-52-3 family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00308864 Functional Category Bioactive
Superfamily Protease and Pol polyprotein Binder Superfamily
Class Class 876

Cousin Family NamesSeedsMembers
Renin Inhibitor Remikiren Family 100 126
Renin Inhibitor Enalkiren Family 56 44
Renin Inhibitor (h-261)boc-his-pro-phe-his-leu(oh)-val-ile-his... 33 41
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-his-agly-ile-v... 3 2
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 50 17
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Pol polyprotein inhibitor penicillin deriv. 71 family 1 2
Pol polyprotein inhibitor AC1LAQE0 family 13 4
Pol polyprotein inhibitor Hydroxyethylene deriv. 12 family 13 10
Pol polyprotein inhibitor (2S)-4-(1H-benzimidazol-2-ylmethyl)-... 1 0
Pol polyprotein inhibitor N-[(3R,4R,5R)-5-[[(2S)-1-(1H-benzimi... 5 4
Pol polyprotein inhibitor propan-2-yl N-[(2S)-1-[[(2S,3S,5R)-3... 6 2
Renin inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3S,5S)-5-(... 2 0
Integrin beta-3 and Integrin alpha-V inhibitor 2-[1-[2-[[4-(1H... 2 8
Renin inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cycl... 3 0
Pol polyprotein and Protease inhibitor 161186-51-2 family 5 0
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[4-[4-[(... 9 7
Lysosomal Pro-X carboxypeptidase inhibitor 9H-fluoren-9-ylmeth... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00308862 CHEMBL424415 Bioactive benzyl N-[(2S)-1-[[(2S,3R,4R)-4-[[4-[[3-(1H-benzimidazol-2-yl)propanoylamino]methyl]phenyl]methylamino]-3-hydroxy-5-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxo-1-phenylpentan-2-yl]amino]-3,3-dimethyl-1-oxobutan-2-yl]carbamate
CFAMM00308866 CHEMBL104612 Bioactive 161186-49-8
CFAMM00308864 CHEMBL317653 Bioactive 161186-52-3

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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