CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2055
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 5-[4-[2,3-bis(hydroxymethyl)-6,7-dimethoxynaphthalen-1-yl]pyridin-2-yl]phenanthridin-6-one family
No. of Seeds 2 No. of Other Members 22
Family Centroid CFAMM00330039 Functional Category Bioactive
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-specific 3',5'-cyclic phosphodiesterase 4B Binder Superfamily
Class Class 513

Cousin Family NamesSeedsMembers
Multidrug resistance protein Inhibitor Tariquidar Family 3 60
Smoothened homolog Inhibitor LDE225 Family 3 76
Platelet-derived growth factor receptor alpha and Platelet-der... 2 17
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Adenosine receptor A1 and Adenosine receptor A3 Ligand 4-metho... 1 16
cAMP-specific 3',5'-cyclic phosphodiesterase 4C and cAMP-speci... 12 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 2
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 6 9
Equilibrative nucleoside transporter 1 inhibitor SureCN9046933... 2 9
Vascular endothelial growth factor receptor 2 and Aurora kinas... 4 3
Aurora kinase A inhibitor AGN-PC-0760BB family 1 1
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 6
Vascular endothelial growth factor receptor 2 ligand 6-(6,7-di... 4 0
Vascular endothelial growth factor receptor 2 and Cytochrome P... 2 1
Inositol monophosphatase 1 and Prelamin-A/C inhibitor GNF-Pf-3... 1 5
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 1 0
Diacylglycerol O-acyltransferase 1 inhibitor 3-[[1-[5-[(3-meth... 1 1
Diacylglycerol O-acyltransferase 1 inhibitor 2-[[4-[5-[(3-meth... 2 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00330039 CHEMBL12346 Bioactive 5-[4-[2,3-bis(hydroxymethyl)-6,7-dimethoxynaphthalen-1-yl]pyridin-2-yl]phenanthridin-6-one
CFAMM00330045 CHEMBL12383 Bioactive SureCN7742049

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

39244 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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