CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2057
Family Name G1/S-specific cyclin-E1 and Cyclin-dependent kinase 2 inhibitor (2S,3S)-3-[[7-(benzylamino)-3-propan-2-ylpyrazolo[1,5-a]pyrimidin-5-yl]amino]butane-1,2,4-triol family
No. of Seeds 1 No. of Other Members 5
Family Centroid CFAMM00162955 Functional Category Bioactive
Superfamily Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibitor Sch 727965 Superfamily
Class Class 1134

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 1 2
Corticotropin-releasing factor receptor 1 Ligand Dmp-695/696 F... 11 20
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Aurora kinase B and Tyrosine-protein kinase Lck Inhibitor CGP-... 2 29
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 63
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 2 5
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 4 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 13
Adenosine receptor A3 and Adenosine receptor A2a ligand SureCN... 8 7
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Adenosine kinase inhibitor N-cyclopropyl-2-[[1-[(2R,3R,4S,5R)-... 4 1
Prothrombin and Survival motor neuron protein inhibitor CHEMBL... 2 14
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 4
Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta ... 2 3
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 3
Tyrosine-protein kinase Mer and Tyrosine-protein kinase recept... 5 3
Casein kinase II subunit alpha inhibitor 2pvj family 3 1
Tyrosine-protein kinase JAK2 inhibitor [4-[[5-(1-ethylpyrazol-... 2 3
Cathepsin K inhibitor 4-[2,2-dimethylpropyl-[[4-(1,2,4-triazol... 2 1
High affinity nerve growth factor receptor ligand SureCN333709... 4 5
Activated CDC42 kinase 1 inhibitor AGN-PC-078WDN family 7 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 26 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26858 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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