CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM20594
Family Name Proto-oncogene tyrosine-protein kinase LCK and Tyrosine-protein kinase Lck inhibitor AGN-PC-03HLBP family
No. of Seeds 3 No. of Other Members 9
Family Centroid CFAMM00456362 Functional Category Bioactive
Superfamily Adenosine receptor A1 and Histone deacetylase 4 Binder Superfamily
Class Class 2338

Cousin Family NamesSeedsMembers
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
C-C chemokine receptor type 4 Ligand N-(naphthalen-1-yl)-4-neo... 5 78
Metabotropic glutamate receptor 5 Ligand 3-chloro-n-(4-methylt... 2 12
Cyclin-dependent kinase 5 Inhibitor 3-(2-phenylthiazol-4-yl)qu... 2 44
Mitogen-activated protein kinase 11 and Mitogen-activated prot... 10 31
Adenosine receptor A1 Ligand N-(4-phenyl-thiazol-2-yl)-benzami... 5 2
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(5-b... 3 9
Adenosine receptor A1 Ligand 4-nitro-n-(4-phenyl-thiazol-2-yl)... 2 38
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 2 5
Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protei... 1 1
Gonadotropin-releasing hormone receptor ligand ethyl N-[4-[4-[... 2 17
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
C-C chemokine receptor type 3 and Cytochrome P450 2D6 ligand (... 49 4
MAP kinase-activated protein kinase 2 inhibitor 2-[(4,4-dimeth... 11 11
Tyrosine-protein kinase Lck inhibitor benzothiazole analog 11 ... 7 13
Tyrosine-protein kinase Lck inhibitor AGN-PC-074MSE family 18 2
Tyrosine-protein kinase Lck inhibitor AGN-PC-03HL8Q family 4 0
Tyrosine-protein kinase Lck inhibitor AGN-PC-03HLHQ family 2 0
Coagulation factor X inhibitor AGN-PC-09QNAS family 2 1
D(2) dopamine receptor and Potassium voltage-gated channel sub... 2 0
Membrane primary amine oxidase inhibitor N-[4-[2-[4-(diaminome... 5 0
Tyrosine-protein kinase Lck inhibitor AGN-PC-074FBQ family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00456364 CHEMBL217195 Bioactive AGN-PC-017RRY
CFAMM00456362 CHEMBL215630 Bioactive AGN-PC-03HLBP
CFAMM00456367 CHEMBL131346 Bioactive AGN-PC-03IO7Y

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46007 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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