CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2070
Family Name Renin inhibitor SureCN1144364 family
No. of Seeds 3 No. of Other Members 15
Family Centroid CFAMM00330135 Functional Category Bioactive with Natural Product
Superfamily Renin and Gamma-aminobutyric acid receptor subunit beta-3 Binder Superfamily
Class Class 297

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dibucaine F... 2 136
Cyclooxygenase Inhibitor Indomethacin Family 6 271
Somatostatin receptor type 2 ligand octapeptide Lanreotide Family 93 156
Hemagglutinin Inhibitor Arbidol Family 1 4
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
Cholecystokinin receptor type A Ligand A-71378 Family 77 23
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
DNA topoisomerase 1 Inhibitor KT6006 Family 3 53
Oestrogen receptor and Estrogen receptor beta Ligand 4-(3-phen... 5 14
Platelet-derived growth factor receptor alpha and Platelet-der... 4 54
Serine/threonine-protein kinase Chk1 and Wee1-like protein kin... 2 101
Neuromedin-K receptor Ligand 3-methoxy-n',2-diphenylquinoline-... 14 33
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
Prostaglandin G/H synthase 2 Inhibitor L-761000 Family 8 44
Phospholipase A2 Inhibitor Hyrtiosulawesine Family 1 3
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 6 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 7 11
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 3 28
Kinesin-like protein KIF11 inhibitor AGN-PC-080PZM family 1 11
Vascular endothelial growth factor receptor 2 ligand indolyl q... 4 3
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 4 14
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 2 21
Renin inhibitor AGN-PC-09M9MJ family 2 23
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
Protein kinase C alpha type and Protein kinase C delta type in... 4 37
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 19
Renin inhibitor [2-(3-fluoro-2,6-dimethylphenoxy)-1-phenylpyrr... 5 12
NS5B protein inhibitor AC1O5AET family 3 1
Glucagon receptor ligand 3-[[4-[(2S)-2-[5-(trifluoromethoxy)-1... 1 2
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Substance-P receptor ligand 1-[4-(2-methoxyphenyl)piperazin-1-... 11 12
Transient receptor potential cation channel subfamily V member... 1 5
Beta-2 adrenergic receptor ligand SureCN5346426 family 8 0
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
Proto-oncogene tyrosine-protein kinase receptor Ret and Vascul... 5 14
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 4 1
Wee1-like protein kinase and Serine/threonine-protein kinase C... 3 51
Wee1-like protein kinase and Serine/threonine-protein kinase C... 8 0
Gonadotropin-releasing hormone receptor ligand SureCN7905635 f... 2 2
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
Substance-P receptor and Neuromedin-K receptor ligand N-[(2R,4... 1 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8
Coagulation factor X and Prothrombin inhibitor SureCN6434488 f... 3 13
Cannabinoid receptor 1 ligand (4-hydroxynaphthalen-1-yl)-[1-(2... 2 0
Vasopressin V2 receptor and Vasopressin V1a receptor ligand Su... 2 2
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 1 8
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 3 2
Mitogen-activated protein kinase 14 inhibitor SureCN4508019 fa... 1 0
Signal transducer and activator of transcription 1-alpha/beta ... 1 36
RAC-alpha serine/threonine-protein kinase and Cyclin-dependent... 1 3
Arachidonate 5-lipoxygenase inhibitor AGN-PC-071TED family 9 12
Kinesin-like protein KIF11 inhibitor AGN-PC-07R5ZC family 1 5
NP (7,8-dimethoxy-3-methyl-2,3-dihydro-1h-benzo[d]azepin-4-yl)... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00330135 CHEMBL1270278 Bioactive SureCN1144364
CFAMM00330141 CHEMBL1236060 Bioactive AGN-PC-072D36
CFAMM00330134 CHEMBL1270277 Bioactive AGN-PC-09M800

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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