CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2073
Family Name Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-PC-0753FS family
No. of Seeds 4 No. of Other Members 15
Family Centroid CFAMM00330179 Functional Category Bioactive
Superfamily Histone deacetylase 2 and Histone deacetylase 1 Binder Superfamily 6
Class Class 2029

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Substance-P receptor Ligand R 673 Family 2 127
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 2-benzyl-6-... 9 80
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-(b... 17 47
Fatty-acid amide hydrolase 1 Inhibitor 1-(oxazolo[4,5-b]pyridi... 19 34
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(pyridin-2-yl)oxaz... 10 142
Cytochrome P450 3A4 Inhibitor 3-(5-((methylthio)methyl)furan-2... 4 14
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-[5-(4-hydroxyphe... 4 36
Fatty-acid amide hydrolase 1 Inhibitor 7-phenyl-1-(5-phenyloxa... 3 3
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(furan-2-yl)oxazol... 2 1
Peroxisome proliferator-activated receptor delta ligand SureCN... 8 19
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 21
Histone deacetylase 1 and Histone deacetylase 2 inhibitor 7-[5... 1 2
Fatty-acid amide hydrolase 1 inhibitor SureCN1471727 family 2 19
Inosine-5'-monophosphate dehydrogenase inhibitor SureCN1318237... 2 12
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 7
Fatty-acid amide hydrolase 1 inhibitor methyl 6-[2-[3-(4-pheny... 8 5
Fatty-acid amide hydrolase 1 inhibitor [(2S)-6-phenoxy-1,2,3,4... 3 6
Neprilysin and Natriuretic peptides A inhibitor (2S)-2-[[1-[[(... 3 3
Fatty-acid amide hydrolase 1 and Liver carboxylesterase 1 inhi... 2 2
Sphingosine 1-phosphate receptor 1 ligand 6-[2-[4-phenyl-3-(tr... 2 3
Sphingosine 1-phosphate receptor 1 ligand AGN-PC-00DWQL family 2 2
Beta-secretase 1 and Cytochrome P450 3A4 inhibitor N-[(2S,3R)-... 3 7
Fatty-acid amide hydrolase 1 inhibitor methyl 5-[2-(7-phenylhe... 2 4
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Collagenase 3 inhibitor AGN-PC-03HW1J family 4 0
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 4jj ... 1 1
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 5a f... 2 1
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 5
Fatty-acid amide hydrolase 1 inhibitor N-methyl-2-[3-[4-(pheno... 1 0
Leukotriene A-4 hydrolase inhibitor SureCN3030546 family 9 1
C-C chemokine receptor type 3 ligand SureCN6338683 family 1 2
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 2 3
Fatty-acid amide hydrolase 1 inhibitor 7-phenyl-1-[5-[6-(2H-te... 2 0
Sodium channel protein type 10 subunit alpha ligand AGN-PC-09M... 1 0
ethyl 2-methyl-5-[[4-(2-phenyl-1,3-oxazol-5-yl)phenyl]methoxy]... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00330167 CHEMBL123905 Bioactive AGN-PC-0753FW
CFAMM00330179 CHEMBL339720 Bioactive AGN-PC-0753FS
CFAMM00330184 CHEMBL127846 Bioactive AGN-PC-0753IN
CFAMM00330176 CHEMBL123626 Bioactive N-hydroxy-7-[5-(4-methoxyphenyl)-1,3-oxazol-2-yl]heptanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27043 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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