CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM20814
Family Name Survival motor neuron protein and Muscleblind-like protein 1 inhibitor CHEMBL1331429 family
No. of Seeds 1 No. of Other Members 10
Family Centroid CFAMM00457223 Functional Category Bioactive with Natural Product
Superfamily Beta-lactamase and Coagulation factor X Binder Superfamily 4
Class Class 2691

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Zucapsacin family 7 177
Endothelin-1 receptor Ligand Atrasentan Family 127 336
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
Tumor necrosis factor Inhibitor Y-39041 Family 9 51
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 24
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 16
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Intercellular adhesion molecule 1 Inhibitor Dehydropipernonali... 5 36
Urotensin-2 receptor Ligand SB-436811 Family 6 71
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
Substance-P receptor ligand AGN-PC-075NSQ family 9 3
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Prelamin-A/C and Beta-lactamase inhibitor CHEMBL1589265 family 1 0
Angiotensin-converting enzyme and Angiotensin-converting enzym... 3 13
Sigma non-opioid intracellular receptor 1 ligand BAS 04057753 ... 5 8
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075X1U ... 2 3
Potassium voltage-gated channel subfamily H member 2 and Melan... 4 22
Sodium-dependent noradrenaline transporter and Sodium-dependen... 6 6
Dipeptidyl peptidase 4 inhibitor SureCN8267584 family 1 1
P2X purinoceptor 7 inhibitor N-(1-adamantylmethyl)-2-chloro-5-... 3 0
Melanocortin receptor 4 ligand [(3R,4S)-4-(4-chlorophenyl)-1-p... 5 8
Kappa-type opioid receptor and Delta-type opioid receptor liga... 1 3
Cannabinoid receptor 1 ligand AGN-PC-03RV6L family 10 3
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 15
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-(1,3-b... 4 2
Chymase inhibitor 1,3-bis[(3-methoxyphenyl)methyl]-1,3-diazeti... 3 1
Muscarinic acetylcholine receptor M3 ligand N-[[3-[3-[(3-methy... 5 2
Dipeptidyl peptidase 4 inhibitor SureCN664019 family 4 5
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07R5XZ family 2 2
Cathepsin K inhibitor (2S)-2-[[2-(3,4-dimethoxyphenyl)acetyl]a... 1 1
Protease inhibitor (2S)-N-[4-(1,3-benzodioxol-5-ylmethylamino)... 1 2
Histone deacetylase 3 and Histone deacetylase 9 inhibitor (E)-... 1 0
Orexin receptor type 2 and Orexin receptor type 1 ligand 2-ben... 1 0
Chymase and Chymotrypsinogen A inhibitor N-[(2S)-4-chloro-3-ox... 1 0
Putative NP ZINC02127056 Family 4 1
3-(3,4-dimethoxyphenyl)-3-[3-(7-methoxy-4,8-dimethyl-2-oxochro... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00457215 CHEMBL180886 Bioactive (E)-N-[(1S)-1-(1,3-benzodioxol-5-yl)ethyl]-3-(2-chlorophenyl)prop-2-enamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27272 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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