CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2096
Family Name Endothelin B receptor and Endothelin-1 receptor ligand SureCN8180058 family
No. of Seeds 6 No. of Other Members 4
Family Centroid CFAMM00330367 Functional Category Bioactive with Natural Product
Superfamily Endothelin-1 receptor Ligand Atrasentan Superfamily
Class Class 954

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Endothelin-1 receptor Ligand Atrasentan Family 127 336
Integrin beta-1 and Integrin alpha-4 inhibitor (3S)-3-(3,4-dim... 5 61
Endothelin-1 receptor and Endothelin B receptor ligand (2R,3R,... 5 4
Neuropeptide S receptor and Survival motor neuron protein liga... 1 2
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 2 13
Angiotensin-converting enzyme and Angiotensin-converting enzym... 3 13
Potassium voltage-gated channel subfamily H member 2 and Melan... 2 12
Integrin beta-3 and Integrin alpha-V inhibitor (3R)-3-(1,3-ben... 5 0
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-(1,3-b... 4 2
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 10 1
Mu-type opioid receptor ligand N-[2-[(2-amino-2-oxoethyl)-[2-(... 1 0
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 2 0
NP 3-((3a's,6a'r)-5'-(benzo[d][1,3]dioxol-5-ylmethyl)-7-chloro... 32 0
spiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole... 32 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00330367 CHEMBL331625 Bioactive SureCN8180058
CFAMM00330373 CHEMBL331066 Bioactive (2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-1-[2-(2,6-diethylanilino)-2-oxoethyl]-2-[4-(2-methoxyethyl)phenyl]pyrrolidine-3-carboxylic acid
CFAMM00330372 CHEMBL332794 Bioactive A192621
CFAMM00330370 CHEMBL333009 Bioactive (2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-1-[2-(2,6-diethylanilino)-2-oxoethyl]-2-(4-propan-2-yloxyphenyl)pyrrolidine-3-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42736 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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