CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2099
Family Name Pol polyprotein inhibitor benzyl (2S)-2-[[[(2S)-3-[cyclopentylmethyl-(4-methoxyphenyl)sulfonylamino]-2-hydroxypropyl]-(2-phenylethyl)carbamoyl]amino]-3-methylbutanoate family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00330393 Functional Category Bioactive
Superfamily Pol polyprotein and Collagenase 3 Binder Superfamily
Class Class 3387

Cousin Family NamesSeedsMembers
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 16
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-benzy... 10 32
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 13
Cathepsin K inhibitor SureCN6578603 family 1 3
Pol polyprotein inhibitor morpholinone scaffold 1 family 5 29
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 4-acety... 9 4
Collagenase 3 and Stromelysin-1 inhibitor 1-N-benzyl-3-N-hydro... 7 15
Matrix metalloproteinase-9 and Collagenase 3 inhibitor N-hydro... 2 1
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 7 12
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 14 27
Pol polyprotein inhibitor AC1LA9K7 family 7 23
Collagenase 3 and 72 kDa type IV collagenase inhibitor (5R)-N-... 7 0
Pol polyprotein inhibitor AC1LA6RA family 4 12
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-1-... 25 6
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 7 1
Collagenase 3 and Stromelysin-1 inhibitor (2R,4S)-N-hydroxy-4-... 7 0
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R,4S)... 3 0
Pol polyprotein inhibitor AC1NQUJL family 10 11
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
Pol polyprotein inhibitor arylsulfonamide 10c family 17 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 2
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand N-[(... 1 0
Bone morphogenetic protein 1 inhibitor benzyl N-[(4R)-4-[1,3-b... 6 25
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 0
Pol polyprotein inhibitor N-[2-Hydroxy-2-(8-Isopropyl-6,9-Diox... 7 6
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 5 2
C-C chemokine receptor type 5 ligand phenyl N-[1-[(3S)-4-[benz... 2 5
Neutrophil collagenase and Interstitial collagenase inhibitor ... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00330396 CHEMBL189903 Bioactive AC1NQUK3
CFAMM00330393 CHEMBL124003 Bioactive benzyl (2S)-2-[[[(2S)-3-[cyclopentylmethyl-(4-methoxyphenyl)sulfonylamino]-2-hydroxypropyl]-(2-phenylethyl)carbamoyl]amino]-3-methylbutanoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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