CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2100
Family Name Kappa-type opioid receptor and Mu-type opioid receptor ligand SureCN719386 family
No. of Seeds 12 No. of Other Members 16
Family Centroid CFAMM00330423 Functional Category Bioactive
Superfamily Mu-type opioid receptor and Oxytocin receptor Binder Superfamily
Class Class 514

Cousin Family NamesSeedsMembers
Benzodiazepine receptor Ligand Clotiazepam Family 1 1
Histone deacetylase 1 and Potassium voltage-gated channel subf... 4 36
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 1
Prelamin-A/C inhibitor CHEMBL1547148 family 1 8
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 7 4
Vasopressin V2 receptor and Vasopressin V1a receptor ligand 2-... 6 9
Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-4-m... 1 0
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Coagulation factor X and Prothrombin inhibitor SureCN14502287 ... 16 5
Histone deacetylase 1 inhibitor SureCN3642893 family 10 23
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 10 0
Oxytocin receptor ligand N-[1-[2-[[(2S)-1-amino-1-oxo-3-thioph... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 7 5
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 3
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 1 0
Serine/threonine-protein kinase 33 inhibitor N-[5-fluoro-2-(3-... 1 3


External ID

Functional Category

Molecule Name

CFAMM00330401 CHEMBL124015 Bioactive AGN-PC-00PMP9
CFAMM00330422 CHEMBL338393 Bioactive N-methyl-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepin-2-yl)ethyl]thiophene-2-carboxamide
CFAMM00330428 CHEMBL2111838 Bioactive N-[2-[(2S)-5-(2-fluorophenyl)-1-methyl-2,3-dihydro-1,4-benzodiazepin-2-yl]ethyl]thiophene-3-carboxamide
CFAMM00330432 CHEMBL127828 Bioactive AGN-PC-0753PF
CFAMM00330427 CHEMBL2111837 Bioactive N-[2-[(2S)-7-chloro-1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepin-2-yl]ethyl]thiophene-2-carboxamide
CFAMM00330415 CHEMBL169703 Bioactive Tifluadom
CFAMM00330426 CHEMBL2111836 Bioactive N-[2-[(2S)-1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepin-2-yl]ethyl]thiophene-2-carboxamide
CFAMM00330413 CHEMBL2448130 Bioactive N-[2-[(2R)-5-(2-fluorophenyl)-1-methyl-2,3-dihydro-1,4-benzodiazepin-2-yl]ethyl]thiophene-3-carboxamide
CFAMM00330425 CHEMBL2448128 Bioactive N-[2-[(2R)-1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepin-2-yl]ethyl]thiophene-2-carboxamide
CFAMM00330419 CHEMBL126688 Bioactive N-[2-(5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-yl)ethyl]thiophene-2-carboxamide
CFAMM00330424 CHEMBL2448129 Bioactive N-[2-[(2R)-7-chloro-1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepin-2-yl]ethyl]thiophene-2-carboxamide
CFAMM00330423 CHEMBL127969 Bioactive SureCN719386

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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