CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2109
Family Name Serine palmitoyltransferase 1 and Serine palmitoyltransferase 2 inhibitor AC1NQTB7 family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00330546 Functional Category Bioactive
Superfamily Neprilysin Inhibitor Candoxatril Superfamily
Class Class 579

Cousin Family NamesSeedsMembers
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Renin Inhibitor Aliskiren Family 28 107
Thymopentin family 20 133
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Plitidepsin family 15 5
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Oxytocin receptor Ligand [mpa1, D-tyr(et)2, D-tic7]ot Family 43 26
Mu-type opioid receptor Ligand H-tyr-d-ala-aic-asp-val-val-gly... 48 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Pol polyprotein inhibitor 180968-31-4 family 8 13
Caspase-1 inhibitor (3S)-3-[[(2S)-4-[2-carboxyethyl(2-phenoxye... 1 3
Glutamate receptor ionotropic, kainate 2 ligand (2S,3S,4S)-4-[... 4 10
Renin inhibitor N-[(2S,4S,5S,7S)-7-[2-(1-acetylpiperidin-4-yl)... 2 1
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Neprilysin inhibitor SureCN389939 family 5 6
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand (5Z,8... 4 2
Angiotensin-converting enzyme 2 and Neprilysin inhibitor (2S)-... 6 1
Renin inhibitor (3S,6R)-6-(cyclohexylmethyl)-7-hydroxy-7-[[(2S... 1 0
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 0
Neprilysin inhibitor (2S)-4-methoxy-2-[[1-[[(1R,2S)-2-(4-metho... 1 0
NS3 and Non-structural protein 4A inhibitor (4S)-4-[[(2S)-3-ca... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00330546 CHEMBL1241090 Bioactive AC1NQTB7
CFAMM00330548 CHEMBL442105 Bioactive 3-[[(2S,5S)-1-cyclohexyl-3-hydroxy-6-methyl-5-[[(2R)-2-methylbutyl]carbamoyl]heptan-2-yl]carbamoyl]-2-hydroxy-4-oxo-5-phenoxypentanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26414 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543