CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2110
Family Name Integrin alpha-4 inhibitor AC1O7HJM family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00330551 Functional Category Bioactive
Superfamily Integrin beta-1 and Integrin alpha-5 Binder Superfamily
Class Class 639

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
Peptide deformylase, mitochondrial inhibitor folic acid analog... 59 98
Prothrombin Inhibitor Dabigatran Family 7 182
Integrin beta-3 Inhibitor Elarofiban Family 28 45
Integrin alpha-V and Integrin beta-3 Inhibitor SB-223245 Family 27 36
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Integrin beta-3 and Integrin alpha-V inhibitor 2-[1-[2-[[4-(1H... 6 2
Integrin beta-1 and Integrin alpha-4 inhibitor (5R)-5-[[(2R)-2... 2 3


External ID

Functional Category

Molecule Name

CFAMM00330550 CHEMBL1241140 Bioactive (5S)-6-[[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[[(2S)-2-[[2-[4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]amino]-6-[[(E)-3-pyridin-3-ylprop-2-enoyl]amino]hexanoyl]amino]-6-oxohexanoic acid
CFAMM00330549 CHEMBL395150 Bioactive (5R)-6-[(1-carbamoylcyclohexyl)amino]-5-[[(2R)-2-[[4-[(2-methylphenyl)carbamoylamino]benzoyl]amino]-6-[[(E)-3-pyridin-3-ylprop-2-enoyl]amino]hexanoyl]amino]-6-oxohexanoic acid
CFAMM00330551 CHEMBL447509 Bioactive AC1O7HJM

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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