CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2113
Family Name Glycogen synthase kinase-3 alpha and Casein kinase II subunit alpha inhibitor 2-[[5-nitro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]benzamide family
No. of Seeds 1 No. of Other Members 16
Family Centroid CFAMM00330561 Functional Category Bioactive
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Inhibitor Bay 80-6946 Superfamily
Class Class 850

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
Tyrosine-protein kinase SYK Inhibitor R788 Family 3 7
Thyroid hormone receptor beta and Cruzipain ligand CHEMBL14730... 1 12
ALK tyrosine kinase receptor and Insulin-like growth factor 1 ... 1 4
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 7 16
Focal adhesion kinase 1 inhibitor AGN-PC-00AVK6 family 1 1
Rho-associated protein kinase 1 inhibitor SureCN4007647 family 8 4
Mast/stem cell growth factor receptor Kit and Serine/threonine... 11 29
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 4 3
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 3 8
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00330561 CHEMBL1241473 Bioactive 2-[[5-nitro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27430 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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