CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM21191
Family Name Dual specificity protein kinase CLK4 and Dual specificity tyrosine-phosphorylation-regulated kinase 1A inhibitor SureCN1675251 family
No. of Seeds 6 No. of Other Members 2
Family Centroid CFAMM00458475 Functional Category Bioactive
Superfamily Dual specificity protein kinase CLK4 and cAMP Binder Superfamily
Class Class 377

Cousin Family NamesSeedsMembers
Alpha-1D adrenergic receptor Ligand Terazosin Family 28 638
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Vascular endothelial growth factor receptor 2 Ligand Cediranib... 8 38
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Sodium-dependent serotonin transporter Inhibitor 4-furan-2-yl-... 2 10
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 2 3
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 5 45
Adenosine kinase inhibitor 5-[3-(4-methoxyphenyl)propyl]-6-[2-... 2 11
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 6 9
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 3 20
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 6 9
Dual specificity protein kinase CLK4 and Dual specificity tyro... 1 14
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Adenosine receptor A1 and Adenosine receptor A3 ligand AGN-PC-... 6 8
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0
Dihydrofolate reductase inhibitor 7-(3,4-dimethoxyphenyl)-6-me... 1 3
Dihydrofolate reductase inhibitor 7-(2-ethoxynaphthalen-1-yl)-... 3 2
Histamine H4 receptor and Histamine H3 receptor ligand 7-(fura... 2 2
Vascular endothelial growth factor receptor 1 and Receptor-typ... 2 11
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 4 0
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 8 1
Cathepsin K and Cathepsin S inhibitor SureCN4135077 family 2 0
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-amin... 4 3
Adenosine receptor A1 and Adenosine receptor A2a ligand N-[4-(... 4 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 1
Adenosine kinase inhibitor SureCN8139139 family 1 1
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075X2R ... 1 3
Receptor tyrosine-protein kinase erbB-2 ligand AGN-PC-03J2ZU f... 1 2
Dual specificity protein kinase CLK4 and Dual specificity prot... 3 6
Dual specificity protein kinase CLK4 and Dual specificity prot... 1 0
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00458482 CHEMBL566900 Bioactive SureCN1675132
CFAMM00458481 CHEMBL1476499 Bioactive SureCN1675357
CFAMM00458477 CHEMBL1357975 Bioactive SureCN1675327
CFAMM00458487 CHEMBL1374544 Bioactive NCGC00010428
CFAMM00458475 CHEMBL1725513 Bioactive SureCN1675251
CFAMM00458486 CHEMBL1473127 Bioactive AGN-PC-072X5E

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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