CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM21251
Family Name Acyl-CoA:cholesterol acyltransferase inhibitor 3-(2-chloro-6-methylpyridin-3-yl)-1-cycloheptyl-1-[[4-(4-fluorophenoxy)phenyl]methyl]urea family
No. of Seeds 4 No. of Other Members 6
Family Centroid CFAMM00458748 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 2A and Beta-lactamase Binder Superfamily
Class Class 3170

Cousin Family NamesSeedsMembers
Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
Epidermal growth factor receptor and Receptor tyrosine-protein... 8 31
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Fatty-acid amide hydrolase 1 Inhibitor BMS-1 Family 5 22
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 10 46
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL14... 2 11
Corticotropin-releasing factor receptor 1 ligand 6-ethyl-3-met... 6 10
Translocator protein inhibitor 2-fluoro-N-[(2-methoxyphenyl)me... 8 27
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 16 19
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 2 7
P2Y purinoceptor 1 inhibitor 1-(4-tert-butylphenyl)-3-[2-(2-pr... 4 14
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 3 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 4 3
Reverse transcriptase/RNaseH inhibitor AC1L9RKO family 2 17
Metabotropic glutamate receptor 5 ligand AGN-PC-09QKER family 1 0
Coagulation factor X and Cationic trypsin inhibitor SureCN6578... 4 11


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00458748 CHEMBL136274 Bioactive 3-(2-chloro-6-methylpyridin-3-yl)-1-cycloheptyl-1-[[4-(4-fluorophenoxy)phenyl]methyl]urea
CFAMM00458740 CHEMBL139173 Bioactive 1-cycloheptyl-3-(2,4-dichloro-6-methylpyridin-3-yl)-1-[[4-(4-fluorophenoxy)phenyl]methyl]urea
CFAMM00458745 CHEMBL265829 Bioactive 1-cycloheptyl-1-[[4-(4-fluorophenoxy)phenyl]methyl]-3-(2-methoxy-6-methylpyridin-3-yl)urea
CFAMM00458744 CHEMBL138214 Bioactive SureCN8811024

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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