CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2132
Family Name 5-hydroxytryptamine receptor 6 ligand 6-chloro-5-[1-(1-methylpiperidin-3-yl)pyrrolo[2,3-b]pyridin-3-yl]sulfonylimidazo[2,1-b][1,3]thiazole family
No. of Seeds 9 No. of Other Members 0
Family Centroid CFAMM00330764 Functional Category Bioactive
Superfamily D(2) dopamine receptor and Interleukin-1 receptor type 1 Binder Superfamily
Class Class 914

Cousin Family NamesSeedsMembers
Cytochrome P450 26A1 Inhibitor Rambazole Family 7 77
Cyclin-dependent kinase 5 Inhibitor 1-phenyl-3-(2-(pyridin-4-y... 3 53
5-hydroxytryptamine receptor 2B and 5-hydroxytryptamine recept... 7 15
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-chlo... 11 20
Hepatocyte growth factor receptor Ligand 3-(phenylsulfonyl)-1h... 17 59
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
NADH-ubiquinone oxidoreductase chain 3 Inhibitor 6-thiophen-3-... 2 0
Neuropeptide Y receptor type 5 ligand N-[[(1S,5R)-3-(1-phenyle... 5 1
5-hydroxytryptamine receptor 6 ligand 3-(5-chlorothiophen-2-yl... 6 1
Mitogen-activated protein kinase 14 and LIM domain kinase 1 in... 4 19
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 3 10
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 5 27
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-0A9RCZ family 7 7
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Adenosine receptor A2b and Adenosine receptor A3 ligand 3-[5-(... 4 2
Serine/threonine-protein kinase Chk1 inhibitor 5-[5-(1-methylp... 3 2
TGF-beta receptor type-1 and Mitogen-activated protein kinase ... 6 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 1
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 2 1
Prostaglandin G/H synthase 2 inhibitor 4-N,4-N-diethyl-2-(4-me... 5 1
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 3 1


External ID

Functional Category

Molecule Name

CFAMM00330770 CHEMBL1242703 Bioactive 6-chloro-5-[1-(1-methylpyrrolidin-3-yl)pyrrolo[2,3-b]pyridin-3-yl]sulfonylimidazo[2,1-b][1,3]thiazole
CFAMM00330763 CHEMBL1242518 Bioactive 6-chloro-5-[1-(1-ethylpiperidin-3-yl)pyrrolo[2,3-b]pyridin-3-yl]sulfonylimidazo[2,1-b][1,3]thiazole
CFAMM00330769 CHEMBL1242702 Bioactive 6-chloro-5-(1-pyrrolidin-3-ylpyrrolo[2,3-b]pyridin-3-yl)sulfonylimidazo[2,1-b][1,3]thiazole
CFAMM00330762 CHEMBL1242615 Bioactive 6-chloro-5-[1-(1-propan-2-ylpiperidin-3-yl)pyrrolo[2,3-b]pyridin-3-yl]sulfonylimidazo[2,1-b][1,3]thiazole
CFAMM00330768 CHEMBL565724 Bioactive AGN-PC-07CP7Y
CFAMM00330767 CHEMBL1242425 Bioactive 6-chloro-5-(1-piperidin-3-ylpyrrolo[2,3-b]pyridin-3-yl)sulfonylimidazo[2,1-b][1,3]thiazole
CFAMM00330766 CHEMBL1242791 Bioactive 6-chloro-5-[1-(1-ethylpyrrolidin-3-yl)pyrrolo[2,3-b]pyridin-3-yl]sulfonylimidazo[2,1-b][1,3]thiazole
CFAMM00330765 CHEMBL565746 Bioactive AGN-PC-07CP85
CFAMM00330764 CHEMBL1242517 Bioactive 6-chloro-5-[1-(1-methylpiperidin-3-yl)pyrrolo[2,3-b]pyridin-3-yl]sulfonylimidazo[2,1-b][1,3]thiazole

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



114000 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543