CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2135
Family Name Vascular endothelial growth factor receptor 2 ligand 7-(6-acetyl-7-methoxyquinolin-4-yl)oxy-N-(4-methylphenyl)-2,3-dihydro-1,4-benzoxazine-4-carboxamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00330783 Functional Category Bioactive
Superfamily Vascular endothelial growth factor receptor 2 Binder Superfamily
Class Class 656

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase B-raf inhibitor diaryl urea an... 12 93
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
Vascular endothelial growth factor receptor 2 Ligand E 7080 Fa... 7 17
Tivozanib family 4 6
Vascular endothelial growth factor receptor 2 Ligand PF-003372... 1 4
Platelet-derived growth factor receptor alpha and Platelet-der... 2 17
Platelet-derived growth factor receptor beta and Epidermal gro... 3 7
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 2-benzyl-6-... 9 80
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
Vascular endothelial growth factor receptor 2 and Aurora kinas... 3 3
Proto-oncogene tyrosine-protein kinase Src inhibitor SureCN525... 8 8
Inosine-5'-monophosphate dehydrogenase 2 inhibitor 7-methoxy-2... 7 1
Prostaglandin E2 receptor EP4 subtype ligand AGN-PC-09QHF0 family 3 1
Cholinesterase and Acetylcholinesterase inhibitor 5-hydroxy-7-... 5 19
Protein-tyrosine kinase 2-beta and Focal adhesion kinase 1 inh... 3 6
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Vascular endothelial growth factor receptor 2 and Tyrosine-pro... 4 0
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 4 4
Substance-P receptor ligand SureCN2139814 family 7 7
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
ATP-binding cassette sub-family G member 2 inhibitor 5-[(4-bro... 1 1


External ID

Functional Category

Molecule Name

CFAMM00330783 CHEMBL1242575 Bioactive 7-(6-acetyl-7-methoxyquinolin-4-yl)oxy-N-(4-methylphenyl)-2,3-dihydro-1,4-benzoxazine-4-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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