CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2136
Family Name 5-hydroxytryptamine receptor 6 ligand 3-(5-chlorothiophen-2-yl)sulfonyl-1-(1-methylpiperidin-3-yl)pyrrolo[2,3-b]pyridine family
No. of Seeds 6 No. of Other Members 1
Family Centroid CFAMM00330787 Functional Category Bioactive
Superfamily D(2) dopamine receptor and Interleukin-1 receptor type 1 Binder Superfamily
Class Class 914

Cousin Family NamesSeedsMembers
Hepatocyte growth factor receptor Ligand 3-(phenylsulfonyl)-1h... 17 59
5-hydroxytryptamine receptor 6 ligand 6-chloro-5-[1-(1-methylp... 9 0
Fatty-acid amide hydrolase 1 inhibitor 5-[5-(4-chlorophenyl)su... 2 4
5-hydroxytryptamine receptor 6 ligand 3-(3-chlorophenyl)sulfon... 8 1
5-hydroxytryptamine receptor 6 ligand 3-(3-bromophenyl)sulfony... 3 0
5-hydroxytryptamine receptor 6 ligand AGN-PC-076AT1 family 7 0
Prostaglandin G/H synthase 2 inhibitor 4-N,4-N-diethyl-2-(4-me... 5 1
5-hydroxytryptamine receptor 6 ligand 8-(1-pyrrolidin-3-ylpyrr... 1 0


External ID

Functional Category

Molecule Name

CFAMM00330788 CHEMBL235118 Bioactive 3-(5-chlorothiophen-2-yl)sulfonyl-1-piperidin-3-ylpyrrolo[2,3-b]pyridine
CFAMM00330787 CHEMBL236812 Bioactive 3-(5-chlorothiophen-2-yl)sulfonyl-1-(1-methylpiperidin-3-yl)pyrrolo[2,3-b]pyridine
CFAMM00330786 CHEMBL1242614 Bioactive 3-(5-chlorothiophen-2-yl)sulfonyl-1-pyrrolidin-3-ylpyrrolo[2,3-b]pyridine
CFAMM00330785 CHEMBL392976 Bioactive 3-(5-chlorothiophen-2-yl)sulfonyl-1-(1-ethylpiperidin-3-yl)pyrrolo[2,3-b]pyridine
CFAMM00330790 CHEMBL583389 Bioactive AGN-PC-07CP7P
CFAMM00330789 CHEMBL394233 Bioactive 3-[(5-chlorothiophen-2-yl)methylsulfonyl]-1-pyrrolidin-3-ylpyrrolo[2,3-b]pyridine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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