CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM21582
Family Name Retinal dehydrogenase 1 and Nuclear receptor ROR-gamma ligand 2-chloro-N-cyclohexyl-N-phenylacetamide family
No. of Seeds 3 No. of Other Members 13
Family Centroid CFAMM00460070 Functional Category Bioactive with Natural Product
Superfamily Retinal dehydrogenase 1 and Ras-related protein Rab-9A Binder Superfamily 2
Class Class 451

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Sodium channel Ligand xylidine derivative Mepivacaine Family 10 114
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Motilin receptor Ligand GSK962040 Family 30 457
Apoptosis regulator Bcl-2 Inhibitor MCI-186 Family 2 25
Tumor necrosis factor Inhibitor Pirfenidone Family 2 38
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Transient receptor potential cation channel subfamily V member... 6 33
Fatty-acid amide hydrolase 1 Inhibitor Phenyl-1,4-bismaleimide... 1 5
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 47
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Acetylcholinesterase Inhibitor (3-hydroxy-2-methyl-phenyl)-tri... 4 25
Aldose reductase Inhibitor (4-methyl-2-oxo-2h-quinolin-1-yl)-a... 1 15
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Anilides Metabolite Alachlor Family 1 8
1-[(4aS,9bR)-2,8-dimethyl-1,2,3,4,4a,9b-hexahydropyrido[4,3-b]... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00460064 CHEMBL1603760 Bioactive 2-Chloro-N,N-diphenylacetamide
CFAMM00460070 CHEMBL1387688 Bioactive 2-chloro-N-cyclohexyl-N-phenylacetamide
CFAMM00460069 CHEMBL1567635 Bioactive N-benzyl-2-chloro-N-phenylacetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27397 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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