CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2162
Family Name Pol polyprotein inhibitor AC1LAPRV family
No. of Seeds 13 No. of Other Members 7
Family Centroid CFAMM00330932 Functional Category Bioactive
Superfamily Pol polyprotein and Collagenase 3 Binder Superfamily
Class Class 3387

Cousin Family NamesSeedsMembers
Pol polyprotein inhibitor AC1LAGJO family 6 1
Neutrophil collagenase and Stromelysin-1 inhibitor 7-[[(2S)-2-... 10 9
Neutrophil collagenase and Stromelysin-1 inhibitor tert-butyl ... 2 0
Pol polyprotein inhibitor SureCN4637317 family 19 6
Pol polyprotein inhibitor AC1L9X2E family 1 2
Pol polyprotein inhibitor N-[2-Hydroxy-2-(8-Isopropyl-6,9-Diox... 7 6
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-acety... 6 7


External ID

Functional Category

Molecule Name

CFAMM00330949 CHEMBL341317 Bioactive AC1LAPS4
CFAMM00330941 CHEMBL288907 Bioactive 4-amino-N-butan-2-yl-N-[(2R)-2-[(3S,6S)-5,8-dioxo-6-propan-2-yl-14-oxa-4,7-diazabicyclo[13.2.2]nonadeca-1(17),15,18-trien-3-yl]-2-hydroxyethyl]benzenesulfonamide
CFAMM00330948 CHEMBL339204 Bioactive AC1LAPSA
CFAMM00330940 CHEMBL297171 Bioactive 4-amino-N-[(2R)-2-[(3S,6S)-5,8-dioxo-6-propan-2-yl-14-oxa-4,7-diazabicyclo[13.2.2]nonadeca-1(17),15,18-trien-3-yl]-2-hydroxyethyl]-N-(2-phenylethyl)benzenesulfonamide
CFAMM00330933 CHEMBL442738 Bioactive PI9
CFAMM00330947 CHEMBL125573 Bioactive AC1LAPS1
CFAMM00330932 CHEMBL125323 Bioactive AC1LAPRV
CFAMM00330946 CHEMBL42715 Bioactive 4-amino-N-[(2R)-2-[(3S,6S)-5,8-dioxo-6-propan-2-yl-14-oxa-4,7-diazabicyclo[13.2.2]nonadeca-1(17),15,18-trien-3-yl]-2-hydroxyethyl]-N-[2-(4-methoxyphenyl)ethyl]benzenesulfonamide
CFAMM00330938 CHEMBL340749 Bioactive AC1LAPRY
CFAMM00330952 CHEMBL125538 Bioactive AC1LAPS7
CFAMM00330937 CHEMBL288008 Bioactive 4-amino-N-cyclopentyl-N-[(2R)-2-[(3S,6S)-5,8-dioxo-6-propan-2-yl-14-oxa-4,7-diazabicyclo[13.2.2]nonadeca-1(17),15,18-trien-3-yl]-2-hydroxyethyl]benzenesulfonamide
CFAMM00330936 CHEMBL42402 Bioactive N-[4-[[(2R)-2-[(3S,6S)-5,8-dioxo-6-propan-2-yl-14-oxa-4,7-diazabicyclo[13.2.2]nonadeca-1(17),15,18-trien-3-yl]-2-hydroxyethyl]-(3-methylbutyl)sulfamoyl]phenyl]acetamide
CFAMM00330950 CHEMBL124423 Bioactive AC1LAPSD

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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