CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2190
Family Name Vascular endothelial growth factor receptor 2 and Fibroblast growth factor receptor 1 ligand AGN-PC-09M5ZH family
No. of Seeds 3 No. of Other Members 11
Family Centroid CFAMM00331181 Functional Category Bioactive
Superfamily Glucokinase and P2X purinoceptor 7 Binder Superfamily
Class Class 1293

Cousin Family NamesSeedsMembers
Receptor tyrosine-protein kinase erbB-2 Inhibitor TAK-285 Family 16 124
RAF proto-oncogene serine/threonine-protein kinase Inhibitor R... 7 148
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 22
Tyrosine-protein kinase Lck inhibitor 4-N-(2-chloro-6-methylph... 8 45
Tyrosine-protein kinase Lck inhibitor AGN-PC-073GX8 family 12 1
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Vascular endothelial growth factor receptor 2 and Fibroblast g... 10 3
Vascular endothelial growth factor receptor 2 ligand AGN-PC-09... 5 11
Vascular endothelial growth factor receptor 2 ligand 1-[4-[6-a... 11 13
Insulin receptor and Insulin-like growth factor 1 receptor lig... 17 7
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 3 0
Receptor tyrosine-protein kinase erbB-2 ligand N-[3-chloro-4-(... 4 3
Receptor tyrosine-protein kinase erbB-2 ligand 2-[2-[4-[3-chlo... 4 5
Rho-associated protein kinase 1 inhibitor SureCN4716133 family 2 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4463897 f... 3 2
Epidermal growth factor receptor and Receptor tyrosine-protein... 8 0
P2Y purinoceptor 1 inhibitor 1-[2-[2-(2-chlorophenyl)-5-methyl... 1 3


External ID

Functional Category

Molecule Name

CFAMM00331181 CHEMBL1254356 Bioactive AGN-PC-09M5ZH
CFAMM00331180 CHEMBL1254355 Bioactive AGN-PC-09M5ZG
CFAMM00331189 CHEMBL1253194 Bioactive AGN-PC-09M5CI

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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