CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2202
Family Name Glucocorticoid receptor and Mineralocorticoid receptor ligand SureCN291473 family
No. of Seeds 5 No. of Other Members 40
Family Centroid CFAMM00331288 Functional Category Bioactive
Superfamily Glucocorticoid receptor and Mineralocorticoid receptor Binder Superfamily
Class Class 1991

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
DNA Binder Elliptinium Acetate Family 11 116
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
D(2) dopamine receptor and D(3) dopamine receptor Ligand L-741... 9 73
Alpha-1A adrenergic receptor Ligand RS-17053 Family 9 6
Adenosine receptor A3 Ligand 4-methoxy-2-phenyl-2h-pyrazolo[4,... 9 49
D(2) dopamine receptor Ligand SLV-314 Family 19 69
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
5-hydroxytryptamine receptor 2A and Alpha-2A adrenergic recept... 4 29
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 18 17
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(1,5-naph... 4 20
Progesterone receptor and Glucocorticoid receptor ligand (5Z)-... 5 2
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 17 69
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 2 10
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 5
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 5
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 2 10
Progesterone receptor and Glucocorticoid receptor ligand SureC... 4 2
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 2 0
Glucocorticoid receptor ligand (2R)-1,1,1-trifluoro-4-(2-metho... 2 5
Glucocorticoid receptor and Progesterone receptor ligand AGN-P... 3 3
Glucocorticoid receptor and Progesterone receptor ligand AGN-P... 9 6
Glucocorticoid receptor ligand 4-fluoro-2-[5,5,5-trifluoro-4-h... 3 9
Survival motor neuron protein inhibitor CHEMBL1379159 family 1 10
5-hydroxytryptamine receptor 2C and Cytochrome P450 1A2 ligand... 6 4
DNA-(apurinic or apyrimidinic site) lyase and Ras-related prot... 1 6
Glucagon receptor and Mitogen-activated protein kinase 14 liga... 6 5
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL15681... 1 5
Somatostatin receptor type 2 ligand SureCN4313450 family 2 25
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
Histone deacetylase 1 and Potassium voltage-gated channel subf... 1 0
Sodium-dependent serotonin transporter inhibitor SureCN7536104... 6 2
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 3 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 2 3
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 4 0
Serine/threonine-protein kinase B-raf inhibitor pyrrole-based ... 2 0
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 5
D(2) dopamine receptor and D(4) dopamine receptor ligand AGN-P... 1 0
Sigma non-opioid intracellular receptor 1 ligand 1'-[4-[1-(4-f... 2 0
Substance-P receptor ligand AGN-PC-00FIT5 family 3 11
Protein kinase C theta type and Protein kinase C delta type in... 10 7
Sodium/hydrogen exchanger 1 inhibitor 2-[(E)-[7-(2-chloropheny... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00331288 CHEMBL1254734 Bioactive SureCN291473
CFAMM00331307 CHEMBL1253819 Bioactive (2R)-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-methyl-2-(1H-pyrrolo[3,2-c]pyridin-2-ylmethyl)pentan-2-ol
CFAMM00331293 CHEMBL1255080 Bioactive SureCN5647236
CFAMM00331289 CHEMBL1254735 Bioactive SureCN290538
CFAMM00331321 CHEMBL1254994 Bioactive SureCN291380

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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