CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2203
Family Name Vascular endothelial growth factor receptor 2 and Fibroblast growth factor receptor 1 ligand AGN-PC-09M4BQ family
No. of Seeds 10 No. of Other Members 3
Family Centroid CFAMM00331332 Functional Category Bioactive
Superfamily Vascular endothelial growth factor receptor 2 and Tyrosine-protein kinase Lyn Binder Superfamily
Class Class 3054

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase B-raf inhibitor diaryl urea an... 12 93
Receptor tyrosine-protein kinase erbB-2 Inhibitor TAK-285 Family 16 124
RAF proto-oncogene serine/threonine-protein kinase Inhibitor R... 7 148
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
Platelet-derived growth factor receptor alpha and Fibroblast g... 3 47
B2 bradykinin receptor Ligand FR-173657 Family 44 180
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 22
Tyrosine-protein kinase Lck inhibitor 4-N-(2-chloro-6-methylph... 8 45
Tyrosine-protein kinase Lck inhibitor AGN-PC-073GX8 family 12 1
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Vascular endothelial growth factor receptor 2 and Fibroblast g... 3 11
Vascular endothelial growth factor receptor 2 ligand AGN-PC-09... 5 11
Neuropeptide Y receptor type 1 ligand 2-[(4-chlorophenoxy)meth... 5 13
Vascular endothelial growth factor receptor 2 ligand 1-[4-[6-a... 11 13
Vascular endothelial growth factor receptor 2 ligand 1-[4-[6-a... 2 0
Epidermal growth factor receptor and Receptor tyrosine-protein... 6 9
Insulin receptor and Insulin-like growth factor 1 receptor lig... 17 7
Insulin-like growth factor 1 receptor and Potassium voltage-ga... 2 2
Dual specificity protein kinase TTK inhibitor 6-N-cyclohexyl-2... 3 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 10 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 0
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 5 7
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 3 0
Receptor tyrosine-protein kinase erbB-2 ligand N-[3-chloro-4-(... 4 3
Receptor tyrosine-protein kinase erbB-2 ligand 2-[2-[4-[3-chlo... 4 5
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 3 0
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 3 0
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 9 3
Rho-associated protein kinase 1 inhibitor SureCN4716133 family 2 2
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 4 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4463897 f... 3 2
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 2 0
Vascular endothelial growth factor receptor 2 and Angiopoietin... 3 3
Epidermal growth factor receptor and Receptor tyrosine-protein... 8 0
Glucagon receptor ligand SureCN2647807 family 3 7
RAF proto-oncogene serine/threonine-protein kinase inhibitor a... 8 6
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 2 0
Acyl-CoA desaturase 1 inhibitor AGN-PC-077KJ2 family 1 0
P2Y purinoceptor 1 inhibitor 1-[2-[2-(2-chlorophenyl)-5-methyl... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00331330 CHEMBL1254277 Bioactive SureCN4285045
CFAMM00331329 CHEMBL1253837 Bioactive AGN-PC-09M7OU
CFAMM00331328 CHEMBL1254190 Bioactive AGN-PC-00QBE5
CFAMM00331334 CHEMBL1255098 Bioactive SureCN4286061
CFAMM00331327 CHEMBL1254193 Bioactive AGN-PC-00JDC1
CFAMM00331333 CHEMBL1253916 Bioactive AGN-PC-09M5VN
CFAMM00331332 CHEMBL1253838 Bioactive AGN-PC-09M4BQ
CFAMM00331325 CHEMBL1254515 Bioactive AGN-PC-09M9UV
CFAMM00331331 CHEMBL1254278 Bioactive SureCN4287158

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48705 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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