CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2213
Family Name Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-fluorophenyl)-1-[(6S)-6-(3-cyanophenyl)-3-bicyclo[4.1.0]heptanyl]-1-[2-[[(2R)-1-hydroxypropan-2-yl]-propan-2-ylamino]ethyl]urea family
No. of Seeds 13 No. of Other Members 6
Family Centroid CFAMM00331460 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 Binder Superfamily 2
Class Class 3520

Cousin Family NamesSeedsMembers
Androgen receptor Ligand YM-175735 Family 30 129
Melanin-concentrating hormone receptor 1 ligand 1-[(6S)-6-(3-c... 7 18
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 8 24
Melanin-concentrating hormone receptor 1 ligand 1-[(6S)-6-(3-c... 2 3
Melanin-concentrating hormone receptor 1 ligand 3-(3-bromophen... 4 0
Melanin-concentrating hormone receptor 1 ligand 1-[[4-[4-(3-cy... 14 23
Melanin-concentrating hormone receptor 1 ligand 1-[2-[4-(3-cya... 3 2
Melanin-concentrating hormone receptor 1 ligand SureCN3845324 ... 7 4
Melanin-concentrating hormone receptor 1 ligand 1-[4-(3-cyanop... 4 9
Melanin-concentrating hormone receptor 1 ligand SureCN14265737... 2 0
Melanin-concentrating hormone receptor 1 ligand N-[2-[4-(3-cya... 3 9
D(3) dopamine receptor and D(2) dopamine receptor ligand RGH-1... 8 0
Melanin-concentrating hormone receptor 1 ligand SureCN14265866... 11 2
Melanin-concentrating hormone receptor 1 ligand SureCN14101999... 3 0
Melanin-concentrating hormone receptor 1 ligand SureCN13655018... 6 23
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00CYMY ... 1 0
Melanin-concentrating hormone receptor 1 ligand 1-[4-chloro-3-... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00331462 CHEMBL229285 Bioactive 3-(3-chloro-4-fluorophenyl)-1-[(3R,6S)-6-(3-cyanophenyl)-3-bicyclo[4.1.0]heptanyl]-1-[[1-(oxan-4-yl)piperidin-4-yl]methyl]urea
CFAMM00331475 CHEMBL1254634 Bioactive 3-(3-chloro-4-fluorophenyl)-1-[(6S)-6-(3-cyanophenyl)-3-bicyclo[4.1.0]heptanyl]-1-[2-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]ethyl]urea
CFAMM00331474 CHEMBL1254635 Bioactive 3-(3-chloro-4-fluorophenyl)-1-[(6S)-6-(3-cyanophenyl)-3-bicyclo[4.1.0]heptanyl]-1-[[1-(oxan-4-yl)piperidin-4-yl]methyl]urea
CFAMM00331461 CHEMBL1254243 Bioactive 3-(3-chloro-4-fluorophenyl)-1-[(6S)-6-(3-cyanophenyl)-3-bicyclo[4.1.0]heptanyl]-1-[2-[[(2S)-1-hydroxypropan-2-yl]-propan-2-ylamino]ethyl]urea
CFAMM00331460 CHEMBL1254242 Bioactive 3-(3-chloro-4-fluorophenyl)-1-[(6S)-6-(3-cyanophenyl)-3-bicyclo[4.1.0]heptanyl]-1-[2-[[(2R)-1-hydroxypropan-2-yl]-propan-2-ylamino]ethyl]urea
CFAMM00331473 CHEMBL229988 Bioactive SureCN14266145
CFAMM00331466 CHEMBL190068 Bioactive 3-(3-chloro-4-fluorophenyl)-1-[(1R,3R,6S)-6-(3-cyanophenyl)-3-bicyclo[4.1.0]heptanyl]-1-[2-[(3R)-3-hydroxypyrrolidin-1-yl]ethyl]urea
CFAMM00331459 CHEMBL1254149 Bioactive 3-(3-chloro-4-fluorophenyl)-1-[(6S)-6-(3-cyanophenyl)-3-bicyclo[4.1.0]heptanyl]-1-[2-[2-hydroxyethyl(propan-2-yl)amino]ethyl]urea
CFAMM00331472 CHEMBL387502 Bioactive SureCN14266050
CFAMM00331465 CHEMBL229112 Bioactive 3-(3-chloro-4-fluorophenyl)-1-[(3R,6S)-6-(3-cyanophenyl)-3-bicyclo[4.1.0]heptanyl]-1-[2-[[(2S)-1-hydroxypropan-2-yl]-propan-2-ylamino]ethyl]urea
CFAMM00331471 CHEMBL375520 Bioactive 3-(3-chloro-4-fluorophenyl)-1-[(3R,6S)-6-(3-cyanophenyl)-3-bicyclo[4.1.0]heptanyl]-1-[2-[[(2R)-1-hydroxypropan-2-yl]-propan-2-ylamino]ethyl]urea
CFAMM00331464 CHEMBL193164 Bioactive 3-(3-chloro-4-fluorophenyl)-1-[(1S,3R,6R)-6-(3-cyanophenyl)-3-bicyclo[4.1.0]heptanyl]-1-[2-[(3R)-3-hydroxypyrrolidin-1-yl]ethyl]urea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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