CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM22146
Family Name Sodium-dependent serotonin transporter and Sodium-dependent dopamine transporter inhibitor 1-[(E)-3-phenylprop-1-enyl]-1,4-diazepane family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00461826 Functional Category Bioactive
Superfamily Sodium-dependent serotonin transporter and Sodium-dependent dopamine transporter inhibitor 1-[(E)-3-phenylprop-1-enyl]-1,4-diazepane Superfamily
Class Class 2578

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor ligand phenethylamine derivative ... 12 283
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Amine oxidase [flavin-containing] B Inhibitor Selegiline Family 6 26
Noradrenergic re-uptake Inhibitor Phentermine Family 2 11
Noradrenergic re-uptake Inhibitor Protriptyline Family 3 25
Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45
Serotonin re-uptake Inhibitor Dexfenfluramine Family 6 31
C-X-C chemokine receptor type 4 Ligand AMD-3100 Family 3 6
Glutamate receptor AMPA subtype and Noradrenaline uptake Ligan... 9 17
Beta-secretase 1 Inhibitor 4-(4-fluorobenzyl)piperidine Family 2 4
D(2) dopamine receptor and D(3) dopamine receptor Ligand (-)-3... 15 19
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 3 6
Sodium-dependent dopamine transporter and Sodium-dependent ser... 8 2
1-[(E)-3-phenylprop-2-enyl]-4-[[(4S)-4-prop-1-en-2-ylcyclohexe... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00461826 CHEMBL142861 Bioactive 1-[(E)-3-phenylprop-1-enyl]-1,4-diazepane

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27037 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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