CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM22166
Family Name 5-hydroxytryptamine receptor 2A and D(2) dopamine receptor ligand 6-[[4-(4-fluorobenzoyl)piperidin-1-yl]methyl]-6,7-dihydro-5H-1-benzofuran-4-one family
No. of Seeds 5 No. of Other Members 3
Family Centroid CFAMM00461917 Functional Category Bioactive
Superfamily DNA-dependent protein kinase catalytic subunit Inhibitor 2-(benzofuran-2-yl)-6-morpholino-4h-pyran-4-one Superfamily
Class Class 769

Cousin Family NamesSeedsMembers
Creatine kinase Inhibitor 5-(4'-benzoylbiphenyl-4-yl)-2-furoic... 2 66
Sodium-dependent dopamine transporter and Sigma non-opioid int... 7 5


External ID

Functional Category

Molecule Name

CFAMM00461915 CHEMBL494702 Bioactive ethyl 6-[[4-(4-fluorobenzoyl)piperidin-1-yl]methyl]-3-methyl-4-oxo-6,7-dihydro-5H-1-benzofuran-2-carboxylate
CFAMM00461914 CHEMBL493069 Bioactive methyl 6-[[4-(4-fluorobenzoyl)piperidin-1-yl]methyl]-4-oxo-6,7-dihydro-5H-1-benzofuran-3-carboxylate
CFAMM00461918 CHEMBL159929 Bioactive 5-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-6,7-dihydro-5H-1-benzofuran-4-one
CFAMM00461917 CHEMBL143022 Bioactive 6-[[4-(4-fluorobenzoyl)piperidin-1-yl]methyl]-6,7-dihydro-5H-1-benzofuran-4-one
CFAMM00461916 CHEMBL494701 Bioactive 6-[[4-(4-fluorobenzoyl)piperidin-1-yl]methyl]-2-phenyl-6,7-dihydro-5H-1-benzofuran-4-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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