CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2217
Family Name Melanin-concentrating hormone receptor 1 ligand 3-(3-bromophenyl)-1-[(6S)-6-(3-cyanophenyl)-3-bicyclo[4.1.0]heptanyl]-1-[2-[di(propan-2-yl)amino]ethyl]urea family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00331483 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 Binder Superfamily 3
Class Class 3523

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Androgen receptor Ligand YM-175735 Family 30 129
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 13
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Melanin-concentrating hormone receptor 1 ligand 1-[(6S)-6-(3-c... 7 18
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 8 24
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 13 6
Melanin-concentrating hormone receptor 1 ligand 1-[(6S)-6-(3-c... 2 3
Melanin-concentrating hormone receptor 1 ligand 1-[2-[4-(3-cya... 3 2
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,3,4-trifluorop... 2 2


External ID

Functional Category

Molecule Name

CFAMM00331486 CHEMBL229877 Bioactive 1-[(3R,6S)-6-(3-bromophenyl)-3-bicyclo[4.1.0]heptanyl]-3-(3,4-difluorophenyl)-1-[2-[di(propan-2-yl)amino]ethyl]urea
CFAMM00331485 CHEMBL387961 Bioactive SureCN14266142
CFAMM00331484 CHEMBL1254798 Bioactive 1-[(6S)-6-(3-bromophenyl)-3-bicyclo[4.1.0]heptanyl]-3-(3,4-difluorophenyl)-1-[2-[di(propan-2-yl)amino]ethyl]urea
CFAMM00331483 CHEMBL1254241 Bioactive 3-(3-bromophenyl)-1-[(6S)-6-(3-cyanophenyl)-3-bicyclo[4.1.0]heptanyl]-1-[2-[di(propan-2-yl)amino]ethyl]urea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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