CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2223
Family Name Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ligand N-[2-(2,6-dimethoxyphenyl)sulfanylethyl]-2-(2-phenylmethoxyphenoxy)ethanamine family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00331530 Functional Category Bioactive
Superfamily Alpha-1D adrenergic receptor and Transporter Binder Superfamily
Class Class 1733

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
5-hydroxytryptamine receptor 1A Ligand MN-305 Family 12 26
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic recept... 2 2
5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic recept... 1 0
Alpha-1A adrenergic receptor and 5-hydroxytryptamine receptor ... 1 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 7
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0


External ID

Functional Category

Molecule Name

CFAMM00331530 CHEMBL1254582 Bioactive N-[2-(2,6-dimethoxyphenyl)sulfanylethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
CFAMM00331528 CHEMBL1254660 Bioactive N-[2-(2,6-dimethoxyphenyl)sulfinylethyl]-2-(2-phenylmethoxyphenoxy)ethanamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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