CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2225
Family Name D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-3-(1,3-benzodioxol-4-yl)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]prop-2-enamide family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00331559 Functional Category Bioactive with Natural Product
Superfamily Prelamin-A/C and Menin Binder Superfamily 2
Class Class 3257

Cousin Family NamesSeedsMembers
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Muscarinic acetylcholine receptor M1 Ligand AC-260584 Family 4 36
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 7 18
Macrophage migration inhibitory factor Inhibitor 3-benzyl-5-me... 10 42
Amine oxidase [flavin-containing] B Inhibitor N-methyl-n-pheny... 6 25
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
Cannabinoid receptor 2 ligand 8-butoxy-N-(2-fluoro-2-phenyleth... 12 7
Transient receptor potential cation channel subfamily V member... 1 5
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 5 13
Poly [ADP-ribose] polymerase 1 inhibitor 6-[1-(2,3-dihydro-1,4... 1 30
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 3 2
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-N... 2 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 3
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 5 0
Neuropeptide S receptor and Survival motor neuron protein liga... 1 2
Potassium voltage-gated channel subfamily H member 2 and Melan... 9 4
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Androgen receptor ligand (2R)-2-ethyl-1-(2,2,2-trifluoroethyl)... 32 6
Melanin-concentrating hormone receptor 1 and Potassium voltage... 3 6
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075X1U ... 2 3
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 4 0
Translocator protein inhibitor [11C]DAA1106 family 15 2
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 6 11
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 7 10
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 13
Beta-secretase 1 inhibitor Coumarin Compound, 10b family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00331559 CHEMBL125459 Bioactive (E)-3-(1,3-benzodioxol-4-yl)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]prop-2-enamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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