CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM22261
Family Name Prelamin-A/C and Microtubule-associated protein tau inhibitor CHEMBL1439063 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00462669 Functional Category Bioactive
Superfamily Vasopressin V2 receptor and Prelamin-A/C Binder Superfamily
Class Class 1375

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
Cannabinoid receptor 1 Ligand 1,3,5-triphenylimidazolidine-2,4... 2 17
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-toly... 6 28
Cholecystokinin receptor type A Ligand VL-0494 Family 1 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZBI0 family 2 16
Disintegrin and metalloproteinase domain-containing protein 17... 1 2
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 15 12
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 5
D(3) dopamine receptor and Alpha-1B adrenergic receptor ligand... 11 8
Prelamin-A/C and Lysine-specific demethylase 4E inhibitor 4-(4... 2 3
Melanin-concentrating hormone receptor 1 ligand 3-chloro-5-[4-... 2 0
Melanocortin receptor 4 ligand N-[(1S)-1-[2-[4-[(3S,4R)-4-(4-c... 26 13
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 1
Nociceptin receptor and Delta-type opioid receptor ligand spir... 25 9
Mu-type opioid receptor and Nociceptin receptor ligand SureCN8... 7 1
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 4 1
Mitogen-activated protein kinase 14 inhibitor 5-(2-chloro-4-fl... 3 0
Melanin-concentrating hormone receptor 1 ligand SureCN13451707... 3 1
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 1 5
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 0
Vascular endothelial growth factor receptor 2 ligand isoindoli... 1 0
Somatostatin receptor type 1 ligand AGN-PC-078XL6 family 9 9
Somatostatin receptor type 1 ligand AGN-PC-078XL4 family 2 0
Calcitonin gene-related peptide type 1 receptor and Dual speci... 4 0
Phospholipase D1 and Phospholipase D2 inhibitor N-[(2S)-1-[4-(... 3 5
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0
C-X-C chemokine receptor type 3 ligand N-[3-[7-chloro-3-[2-(4-... 1 0
Aldose reductase inhibitor Spiro-cimqat family 6 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00462671 CHEMBL148126 Bioactive 1-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-3-fluoren-9-ylidenepyrrolidine-2,5-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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