CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM22273
Family Name cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhibited 3',5'-cyclic phosphodiesterase A inhibitor 1,6-Naphthyridin-2(1H)-one, 5-ethyl- family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00462705 Functional Category Bioactive
Superfamily Inositol monophosphatase 1 and DNA-(apurinic or apyrimidinic site) lyase Binder Superfamily
Class Class 487

Cousin Family NamesSeedsMembers
Citric Acid family 2 58
Adenosine receptor A3 Ligand 4-methoxy-2-phenyl-2h-pyrazolo[4,... 9 49
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 13 26
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 12
Oestrogen receptor and Estrogen receptor beta Ligand Estrogen ... 7 2
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3,3'-pyrazine-2,5-... 2 14
Indoleamine 2,3-dioxygenase 1 Inhibitor 5-aminoquinolin-8-ol F... 3 16
DNA topoisomerase 1 Inhibitor 3-(4-phenyl-2,4'-bipyridin-6-yl)... 4 13
Androgen receptor Ligand 11-methyl-6,11-dihydro-5h-benzo[a]car... 7 9
Metabotropic glutamate receptor 5 Ligand 7-(3,5-dimethoxypheny... 2 7
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 9 22
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 8 10
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 10
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 33 5
D(4) dopamine receptor ligand AGN-PC-00SXAZ family 2 4
Proto-oncogene tyrosine-protein kinase receptor Ret ligand Sur... 1 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 10 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 7 1
Poly [ADP-ribose] polymerase 1 inhibitor N-(6-oxo-5H-benzo[c][... 1 3
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-074... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00462705 CHEMBL144015 Bioactive 1,6-Naphthyridin-2(1H)-one, 5-ethyl-
CFAMM00462706 CHEMBL144682 Bioactive SureCN10813255

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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