CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2228
Family Name D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-PC-080Z03 family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00275956 Functional Category Bioactive
Superfamily D(2) dopamine receptor and Estrogen receptor Binder Superfamily
Class Class 3526

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Histamine H1 receptor Ligand Mepyramine Family 5 65
Tyrosine kinase Inhibitor PKI166 Family 17 198
Tissue-type plasminogen activator Inhibitor N-(7-benzyloxy-iso... 4 37
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 12 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
Metabotropic glutamate receptor 5 Ligand (3-ethoxy-pyridin-2-y... 3 12
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3,3'-pyrazine-2,5-... 2 14
DNA topoisomerase 1 Inhibitor 3-(4-phenyl-2,4'-bipyridin-6-yl)... 4 13
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
5-hydroxytryptamine receptor 1A Ligand CP-293019 Family 9 24
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 38 35
Androgen receptor Ligand 11-methyl-6,11-dihydro-5h-benzo[a]car... 7 9
Adenosine receptor A1 and Adenosine receptor A2a ligand NSC658... 8 54
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 19 11
Reverse transcriptase/RNaseH inhibitor AC1MHDM5 family 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor Sure... 14 8
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 9 10
Corticotropin-releasing factor receptor 1 ligand 8-(2-chloro-4... 13 1
Lysine--tRNA ligase inhibitor 4-[[[2-(2-piperazin-1-ylpyridin-... 2 1
D(4) dopamine receptor ligand (1Z)-1-hydroxyimino-1-(3-methylp... 1 5
TRAF2 and NCK-interacting protein kinase inhibitor 4-methoxy-3... 4 1
D(1A) dopamine receptor and D(2) dopamine receptor ligand (6aR... 3 6
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 10
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 0
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase inhibitor 1-... 1 3
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 3 2
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 2
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 7 1
D(1A) dopamine receptor and D(2) dopamine receptor ligand (6aS... 2 1
D(2) dopamine receptor and D(1A) dopamine receptor ligand (6aS... 1 0
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 2 8


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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