CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2231
Family Name Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ligand N-[2-(2-chloro-6-methoxyphenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00331595 Functional Category Bioactive
Superfamily Huntingtin and Beta-1 adrenergic receptor Binder Superfamily
Class Class 60

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Beta-1 adrenergic receptor Ligand Nebivolol Family 5 22
5-hydroxytryptamine receptor 1A Ligand MN-305 Family 12 26
5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 2 5
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 2 3
D(4) dopamine receptor ligand AGN-PC-0073PO family 7 10
5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic recept... 1 0
Alpha-1A adrenergic receptor and 5-hydroxytryptamine receptor ... 1 0
D(4) dopamine receptor and D(3) dopamine receptor ligand N-[2-... 6 15
5-hydroxytryptamine receptor 1A and Sodium-dependent noradrena... 5 4
Sodium-dependent serotonin transporter and Sodium-dependent no... 6 21
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 14 1
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 2
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 5
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 0
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00331595 CHEMBL1254828 Bioactive N-[2-(2-chloro-6-methoxyphenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
CFAMM00331594 CHEMBL1255002 Bioactive N-[2-(2,6-dichlorophenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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