CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2238
Family Name Alpha-1A adrenergic receptor and 5-hydroxytryptamine receptor 1A ligand 2-[2-[2-(2-phenylmethoxyphenoxy)ethylamino]ethoxy]benzene-1,3-diol family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00231704 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A Ligand MN-305 Superfamily
Class Class 576

Cousin Family NamesSeedsMembers
Beta-2 adrenergic receptor Ligand Bambuterol Family 4 9
Serotonin re-uptake Inhibitor Paroxetine Family 6 19
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Beta-1 adrenergic receptor Ligand Nebivolol Family 5 22
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
5-hydroxytryptamine receptor 1A Ligand MN-305 Family 12 26
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Oxi4503 family 4 27
Acolbifene family 10 115
Arachidonate 5-lipoxygenase Inhibitor Bw A360C Family 12 8
Platelet-activating factor receptor Ligand L-652731 Family 5 116
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Tubulin beta chain Inhibitor Combretastatin Family 3 5
Beta-secretase 1 Inhibitor Eckol Family 6 40
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 2 3
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 4 10
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 2 2
5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic recept... 2 2
5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic recept... 1 0
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 2 2
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 3
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 7 4
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 7
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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