CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM22383
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor SureCN1388274 family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00463142 Functional Category Bioactive
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor SureCN1388274 Superfamily
Class Class 719

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 5 209
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Endothelin-1 receptor Ligand Atrasentan Family 127 336
Substance-P receptor Ligand DA-5018 Family 14 73
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 16
cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor 4-(3... 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor meth... 1 0
Putative NP ZINC14589285 Family 2 1
Putative NP ZINC04041531 Family 40 0


External ID

Functional Category

Molecule Name

CFAMM00463136 CHEMBL144823 Bioactive (7R,7aS)-7-(3-cyclopentyloxy-4-methoxyphenyl)-5,6,7,7a-tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-one
CFAMM00463142 CHEMBL302632 Bioactive SureCN1388274
CFAMM00463140 CHEMBL59386 Bioactive SureCN1388090
CFAMM00463139 CHEMBL145919 Bioactive methyl (3S,4S)-4-(3-cyclopentyloxy-4-methoxyphenyl)-3-(hydroxymethyl)-3-methylpyrrolidine-1-carboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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