CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2239
Family Name Type-1A angiotensin II receptor and Type-1B angiotensin II receptor ligand SureCN9166107 family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00331624 Functional Category Bioactive
Superfamily Type-1 angiotensin II receptor and Type-2 angiotensin II receptor Binder Superfamily 7
Class Class 3528

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Losartan Family 3 90
Type-1 angiotensin II receptor Ligand Olmesartan Family 13 65
Type-1 angiotensin II receptor Ligand Forasartan Family 3 253
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Type-2 angiotensin II receptor Ligand SC-55634 Family 8 5
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Smoothened homolog inhibitor SureCN1091571 family 2 2
C-X-C chemokine receptor type 4 and Envelope glycoprotein gp16... 2 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 27
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 6
Type-1B angiotensin II receptor ligand SureCN683399 family 3 0
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL14574... 1 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 9 6
Type-1 angiotensin II receptor and Peroxisome proliferator-act... 6 0
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 4 2
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 1 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 5
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
B1 bradykinin receptor ligand N-[4-chloro-2-[[(1R)-1-[4-[3-flu... 5 5
Type-1 angiotensin II receptor ligand 5-[2-[4-[[4-butyl-3-[[4-... 4 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 3 0
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 10 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 35 14
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 8 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 9 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 5 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 2 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 5
Type-1 angiotensin II receptor ligand 2-[(2-ethyl-5,7-dimethyl... 5 3
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 1 0
Alpha-1A adrenergic receptor and Alpha-2A adrenergic receptor ... 3 0
Glycogen synthase kinase-3 beta inhibitor 1-(4-amino-1,2,5-oxa... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00331622 CHEMBL125818 Bioactive SureCN9166337
CFAMM00331628 CHEMBL421074 Bioactive SureCN9163031
CFAMM00331627 CHEMBL125940 Bioactive SureCN9163015
CFAMM00331624 CHEMBL125542 Bioactive SureCN9166107

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

25238 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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