CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2250
Family Name Prostaglandin E2 receptor EP3 subtype and D(2) dopamine receptor ligand AGN-PC-00F98A family
No. of Seeds 2 No. of Other Members 24
Family Centroid CFAMM00318720 Functional Category Bioactive
Superfamily Peroxisome proliferator-activated receptor gamma and Prostacyclin receptor Binder Superfamily
Class Class 2011

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Leukotriene B4 receptor 1 ligand AGN-PC-04XMB7 family 3 18
Retinoic acid receptor RXR-alpha and Retinoic acid receptor RX... 12 10
Retinoic acid receptor gamma and Retinoic acid receptor alpha ... 1 5
Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 7
Free fatty acid receptor 1 ligand 3-[4-[[3-[4-(1,1-dioxothian-... 3 0
Endothelin-1 receptor and Endothelin B receptor ligand AGN-PC-... 4 12
Peroxisome proliferator-activated receptor delta and Peroxisom... 4 5
Cysteinyl leukotriene receptor 1 ligand 4-[(E)-1-carboxy-6-[4-... 2 9
Prostaglandin E2 receptor EP1 subtype and Thromboxane A2 recep... 1 9
Tyrosine-protein phosphatase non-receptor type 1 ligand 2-[4-[... 12 9
Tyrosine-protein phosphatase non-receptor type 1 ligand (2R)-2... 2 0
Tyrosine-protein phosphatase non-receptor type 1 ligand (2R)-2... 8 1


External ID

Functional Category

Molecule Name

CFAMM00331934 CHEMBL234589 Bioactive 2-[6-[[4-[[4-(trifluoromethyl)phenoxy]methyl]phenyl]methoxy]-1-benzothiophen-3-yl]acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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