CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2252
Family Name Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-074O4N family
No. of Seeds 7 No. of Other Members 12
Family Centroid CFAMM00307928 Functional Category Bioactive
Superfamily Collagenase 3 and Matrix metalloproteinase-9 Binder Superfamily 4
Class Class 2303

Cousin Family NamesSeedsMembers
G protein-activated inward rectifier potassium channel 4 ligan... 6 9
ATP-sensitive inward rectifier potassium channel 10 Ligand Gli... 1 2
5-hydroxytryptamine receptor Ligand Bay X3702 Family 3 12
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
Disintegrin and metalloproteinase domain-containing protein 17... 25 33
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 2 55
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 2-[benz... 9 9
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 7
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 5-bromo... 2 1
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 16
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-benzy... 10 32
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 13
Disintegrin and metalloproteinase domain-containing protein 17... 2 8
Disintegrin and metalloproteinase domain-containing protein 17... 10 39
Cathepsin K inhibitor SureCN6578603 family 1 3
Integrin beta-3 and Integrin alpha-IIb inhibitor (2R)-2-(benze... 4 13
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 4-acety... 9 4
Collagenase 3 and Matrix metalloproteinase-9 inhibitor (4R)-N-... 13 4
Pol polyprotein inhibitor benzyl (2S)-2-[[[(2S)-3-[cyclopentyl... 2 6
Collagenase 3 and Stromelysin-1 inhibitor 1-N-benzyl-3-N-hydro... 7 15
Matrix metalloproteinase-9 and Collagenase 3 inhibitor N-hydro... 2 1
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 12
Lethal(3)malignant brain tumor-like protein 1 inhibitor CHEMBL... 1 5
Neutrophil collagenase and Stromelysin-1 inhibitor 7-[[(2S)-2-... 10 9
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 14 27
Pol polyprotein inhibitor AC1LA9K7 family 7 23
Collagenase 3 and 72 kDa type IV collagenase inhibitor (5R)-N-... 7 0
Neutrophil collagenase inhibitor (3R)-2-[4-[4-(dimethylamino)p... 2 4
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-044L... 2 0
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-1-... 25 6
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 7 1
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R,4S)... 3 0
Matrix metalloproteinase-15 and Matrix metalloproteinase-16 in... 1 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4Z)... 17 0
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Stromelysin-1 and Matrix metalloproteinase-9 inhibitor AGN-PC-... 26 12
Pol polyprotein inhibitor AC1NQUJL family 10 11
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
Collagenase 3 and 72 kDa type IV collagenase inhibitor 4-[4-[4... 4 4
Collagenase 3 and 72 kDa type IV collagenase inhibitor AGN-PC-... 3 5
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 19 11
Disintegrin and metalloproteinase domain-containing protein 17... 5 2
Collagenase 3 and Disintegrin and metalloproteinase domain-con... 4 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 2
Disintegrin and metalloproteinase domain-containing protein 17... 25 5
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 4 6
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 0
Collagenase 3 and Neutrophil collagenase inhibitor (3R)-1-hydr... 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 12 1
Disintegrin and metalloproteinase domain-containing protein 17... 9 3
Disintegrin and metalloproteinase domain-containing protein 17... 3 3
Bone morphogenetic protein 1 inhibitor benzyl N-[(4R)-4-[1,3-b... 6 25
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-[(4-b... 3 1
Beta-secretase 1 and Cathepsin B inhibitor N-[(2S)-1-[[(2S,3R)... 2 1
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 0
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltra... 2 1
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 13 3
Disintegrin and metalloproteinase domain-containing protein 17... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 3 1
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 8 6
Neutrophil elastase inhibitor 2-[3-[(4-methoxyphenyl)sulfonyla... 1 0
Carbonic anhydrase 2 and Carbonic anhydrase 9 inhibitor zinc;4... 4 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 6 2
Collagenase 3 and Matrix metalloproteinase-9 inhibitor AGN-PC-... 2 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor N-hydro... 3 1
Neutrophil collagenase and Interstitial collagenase inhibitor ... 3 0
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 2 2
Pol polyprotein inhibitor AC1LA9KP family 1 0
Collagenase 3 and Disintegrin and metalloproteinase domain-con... 1 0
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 2 1
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-acety... 6 7
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzo... 6 7
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 2
72 kDa type IV collagenase and Collagenase 3 inhibitor 2-[[2-(... 2 0
72 kDa type IV collagenase and Interstitial collagenase inhibi... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(3S)-2... 2 2
Histone deacetylase 1 inhibitor (E)-N-hydroxy-3-[2-(3-methoxyp... 1 0
Bone morphogenetic protein 1 inhibitor (2R)-2-[(4-bromophenyl)... 1 4
Integrin alpha-V inhibitor (2R)-3-[(2-methoxybenzoyl)amino]-2-... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00331962 CHEMBL329558 Bioactive N-hydroxy-1-(4-methoxyphenyl)sulfonyl-4-[4-(trifluoromethoxy)benzoyl]-1,4-diazepane-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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