CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2255
Family Name Leukotriene B4 receptor 1 ligand AGN-PC-00GEAR family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00331979 Functional Category Bioactive
Superfamily Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 Binder Superfamily 4
Class Class 2572

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Microsomal triglyceride transfer protein large subunit Inhibit... 3 103
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
P2X purinoceptor 3 Inhibitor A-317491 Family 1 2
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Peroxisome proliferator-activated receptor gamma and Peroxisom... 2 4
Histamine H3 receptor Ligand A-349821 Family 49 228
Interstitial collagenase Inhibitor N-hydroxycarbamoylmethyl-4-... 5 24
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Caspase-3 Inhibitor 2-(4-methoxy-benzyl)isoquinoline-1,3,4-tri... 2 2
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Arachidonate 5-lipoxygenase Inhibitor 2-(4-butoxy-phenyl)-n-hy... 3 9
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Peroxisome proliferator-activated receptor gamma and Peroxisom... 1 0
Peroxisome proliferator-activated receptor delta and Peroxisom... 20 8
Vasopressin V1a receptor and Vasopressin V2 receptor ligand [4... 4 7
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 2 0
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 8 12
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745OX family 2 0
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 10 8
Prothrombin inhibitor N-cyclohexyl-3-[3-(diaminomethylideneami... 3 4
Prelamin-A/C and Retinal dehydrogenase 1 inhibitor CHEMBL15810... 1 1
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 12 0
Growth hormone secretagogue receptor type 1 ligand 2-(2-acetyl... 2 0
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S)... 3 1
Prostaglandin D2 receptor 2 and Chemoattractant receptor-homol... 1 1
Free fatty acid receptor 1 ligand 3-[4-[[3-[2,6-dimethyl-4-[3-... 1 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 15 4
Peroxisome proliferator-activated receptor delta and Peroxisom... 13 0
Caspase-1 inhibitor (3S)-3-[2-[3-(naphthalene-1-carbonylamino)... 13 5
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 2
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-04X9O... 2 1
Free fatty acid receptor 1 ligand (3R,4R)-3-[4-(3,4-dimethylph... 4 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 i... 1 12
Arachidonate 5-lipoxygenase inhibitor methyl 5-[1-(2-butyl-1-b... 2 4
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 4 3
Metabotropic glutamate receptor 2 ligand SureCN787402 family 1 8
Arachidonate 5-lipoxygenase and Arachidonate 15-lipoxygenase i... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00331979 CHEMBL125611 Bioactive AGN-PC-00GEAR
CFAMM00331978 CHEMBL333079 Bioactive N-methyl-N-(2-phenylethyl)-2-[5-phenylmethoxy-3-[(E)-2-(5H-tetrazol-5-yl)ethenyl]naphthalen-1-yl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26858 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543