CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2263
Family Name Bloom syndrome protein inhibitor SR 57227A family
No. of Seeds 2 No. of Other Members 12
Family Centroid CFAMM00331997 Functional Category Bioactive
Superfamily Bloom syndrome protein inhibitor SR 57227A Superfamily
Class Class 2331

Cousin Family NamesSeedsMembers
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 32
Scytalone dehydratase Inhibitor Isoquinolin-1-yl-(3-phenyl-pro... 4 9
Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... 17 29
Cyclin-dependent kinase 2 and Mitogen-activated protein kinase... 7 30
Cathepsin K Inhibitor 2-cyclohexylamino-pyridine-2-carbonitril... 1 2
Transient receptor potential cation channel subfamily V member... 2 26
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-amin... 4 11
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 9 24
Oestrogen receptor Ligand 4-benzyl-2,6-diisobutylamino-pyrimid... 5 37
Histamine H4 receptor Ligand A-943931 Family 14 11
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Macrophage migration inhibitory factor Inhibitor 1-(2-chloroph... 2 22
Sodium-dependent serotonin transporter Inhibitor 6-nitroquipaz... 18 21
Sodium-dependent serotonin transporter Inhibitor 6-chloro-2-pi... 5 35
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Reverse transcriptase Inhibitor PT-109 Family 6 7
Toll-like receptor 7 ligand 6-amino-2-(butylamino)-9-[[4-(dime... 5 4
Histamine H4 receptor ligand 4-[(3R)-3-(methylamino)pyrrolidin... 7 6
Corticotropin-releasing factor receptor 1 ligand 5-(2,4-dichlo... 5 17
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 10
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 1
Acetylcholinesterase and Cholinesterase inhibitor 2-amino-6-[3... 1 4
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 2 1
Nitric oxide synthase, brain and Nitric oxide synthase, induci... 2 0
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00331997 CHEMBL1256322 Bioactive SR 57227A

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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