CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2268
Family Name Receptor tyrosine-protein kinase erbB-2 and Insulin-like growth factor 1 receptor ligand AGN-PC-09M7M1 family
No. of Seeds 4 No. of Other Members 10
Family Centroid CFAMM00332041 Functional Category Bioactive
Superfamily Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibitor A-420983 Superfamily
Class Class 1070

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase mTOR Inhibitor INK128 Family 2 15
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 4 32
Histamine H3 receptor ligand 2-(4-piperidin-1-ylpiperidin-1-yl... 1 3
Insulin-like growth factor 1 receptor ligand SureCN6107989 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00332041 CHEMBL1256425 Bioactive AGN-PC-09M7M1
CFAMM00332050 CHEMBL1256432 Bioactive AGN-PC-09M4IG
CFAMM00332056 CHEMBL1257998 Bioactive SureCN5801190
CFAMM00332053 CHEMBL1256435 Bioactive AGN-PC-09M7O6

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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