CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2269
Family Name Serine/threonine-protein kinase mTOR and DNA-dependent protein kinase catalytic subunit inhibitor Torin 1 family
No. of Seeds 6 No. of Other Members 7
Family Centroid CFAMM00160524 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase mTOR and DNA-dependent protein kinase catalytic subunit Binder Superfamily
Class Class 840

Cousin Family NamesSeedsMembers
D(3) dopamine receptor Ligand SB-277011 Family 13 178
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
JAK Inhibitor Momelotinib Family 33 83
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 10 7
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 2 4
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 11 20
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 13 1
Melanin-concentrating hormone receptor 1 ligand AGN-PC-072CVE ... 4 4
Melanin-concentrating hormone receptor 1 ligand AGN-PC-09M6QF ... 3 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 2
Serine/threonine-protein kinase mTOR inhibitor AGN-PC-093LHN f... 3 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 2
Hepatocyte growth factor receptor ligand AGN-PC-08XYH0 family 8 4
Renin and Potassium voltage-gated channel subfamily H member 2... 9 2
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 3 1
Egl nine homolog 1 inhibitor 1'-[(3-methylpyridin-2-yl)methyl]... 6 4
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 3 2
Serine/threonine-protein kinase Chk1 inhibitor SureCN14402832 ... 6 5
Glucocorticoid receptor ligand 3,3,3-trifluoro-N-[(3S)-3-[1-(4... 10 4
CGMP-dependent protein kinase inhibitor 1-[4-acetyl-3-[[4-[5-(... 2 0
Serine/threonine-protein kinase mTOR inhibitor SureCN7919590 f... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00332057 CHEMBL1256462 Bioactive AGN-PC-087TYY
CFAMM00332063 CHEMBL1256458 Bioactive SureCN6874995
CFAMM00332059 CHEMBL1256469 Bioactive AGN-PC-07BUKZ
CFAMM00332065 CHEMBL1256456 Bioactive SureCN6874774

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26224 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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