CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2271
Family Name Renin inhibitor AGN-PC-04XLXA family
No. of Seeds 9 No. of Other Members 5
Family Centroid CFAMM00332074 Functional Category Bioactive
Superfamily Renin Binder Superfamily 5
Class Class 3539

Cousin Family NamesSeedsMembers
Renin inhibitor AGN-PC-07ZC01 family 12 16
Renin inhibitor SureCN1472318 family 4 1
Renin inhibitor AGN-PC-04XM0H family 3 0
Renin and Cytochrome P450 3A4 inhibitor (3R,4S)-N-[[2-chloro-5... 28 3
Renin and Potassium voltage-gated channel subfamily H member 2... 17 2


External ID

Functional Category

Molecule Name

CFAMM00332084 CHEMBL1256492 Bioactive SureCN8071288
CFAMM00332077 CHEMBL1957798 Bioactive N-[2-[2-[4-[(2S)-1-amino-3-[4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl]propan-2-yl]-3-methylphenyl]phenyl]ethyl]acetamide;hydrochloride
CFAMM00332083 CHEMBL1256493 Bioactive AGN-PC-09M6UV
CFAMM00332076 CHEMBL1258168 Bioactive SureCN8063069
CFAMM00332082 CHEMBL1256491 Bioactive SureCN2542521
CFAMM00332075 CHEMBL1257824 Bioactive AGN-PC-04XLXB
CFAMM00332081 CHEMBL1256489 Bioactive AGN-PC-04XM0G
CFAMM00332074 CHEMBL1257701 Bioactive AGN-PC-04XLXA
CFAMM00332080 CHEMBL1256488 Bioactive AGN-PC-04XLXC

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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