CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM22812
Family Name Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 inhibitor AGN-PC-075RLR family
No. of Seeds 4 No. of Other Members 6
Family Centroid CFAMM00464505 Functional Category Bioactive
Superfamily Retinoic acid receptor RXR-alpha and MO15-related protein kinase Pfmrk Binder Superfamily
Class Class 1913

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Meclofenamic Acid Family 4 11
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Peroxisome proliferator-activated receptor gamma and Retinoic ... 4 9
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Phospholipase D1 Inhibitor Halopemide Family 17 111
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(2,4... 3 6
Metabotropic glutamate receptor 5 Ligand N-(3-acetamidophenyl)... 4 20
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-toly... 6 28
D(2) dopamine receptor Ligand PD-168077 Family 6 5
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
D(3) dopamine receptor and Alpha-1B adrenergic receptor ligand... 11 8
Cellular tumor antigen p53 and Inositol monophosphatase 1 inhi... 1 12
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 8 1
Melanocortin receptor 4 ligand (3R)-N-[(2R)-3-(4-chlorophenyl)... 6 9
Melanin-concentrating hormone receptor 1 and Potassium voltage... 2 2
Melanocortin receptor 4 ligand SureCN6183720 family 2 5
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
Substance-P receptor and Substance-K receptor ligand AGN-PC-07... 5 2
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
Histamine H3 receptor ligand AGN-PC-0CW63F family 1 1
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
Coagulation factor X inhibitor N-(4-chlorophenyl)-2-[[4-(2-oxo... 2 0
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 2
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 8
C-C chemokine receptor type 5 ligand AC1MHPA7 family 2 2
Cannabinoid receptor 1 ligand SureCN14463736 family 2 0
C-C chemokine receptor type 5 ligand AC1MHP8Y family 1 0
Interleukin-8 inhibitor 2-[2-(2,6-dichloroanilino)phenyl]-N-me... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00464508 CHEMBL149213 Bioactive AGN-PC-04S30I
CFAMM00464505 CHEMBL148931 Bioactive AGN-PC-075RLR
CFAMM00464504 CHEMBL356203 Bioactive AGN-PC-075RLP
CFAMM00464510 CHEMBL148629 Bioactive AGN-PC-04S30M

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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