CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2290
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform inhibitor AGN-PC-09M6OZ family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00332269 Functional Category Bioactive
Superfamily Corticotropin-releasing factor receptor 1 Ligand GW876008 Superfamily
Class Class 1070

Cousin Family NamesSeedsMembers
MK-6096 family 3 69
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Progesterone receptor Ligand GSK-1564023A Family 1 11
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 28
Adenosine receptor A3 ligand AGN-PC-07N4XZ family 4 11
Serine/threonine-protein kinase PLK1 and Serine/threonine-prot... 14 42
Adenosine receptor A3 ligand CHEMBL1834696 family 5 18
Fibroblast growth factor receptor 1 and Vascular endothelial g... 3 16
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 1 0
Tyrosine-protein kinase JAK2 and Cytochrome P450 1A2 inhibitor... 1 0
Vascular endothelial growth factor receptor 2 and Serine/threo... 6 13
Adenosine receptor A1 ligand ethyl 1-(2-chloro-2-phenylethyl)-... 5 1
Mast/stem cell growth factor receptor Kit and Epithelial disco... 3 0
Adenosine receptor A2a and Cytochrome P450 3A4 ligand N-[6-(3,... 5 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Tyrosine-protein kinase JAK2 inhibitor 4-[[8-(4-methoxyphenyl)... 2 1
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 4 4
Tyrosine-protein kinase Lck inhibitor AGN-PC-07R5ZB family 4 3
Mitogen-activated protein kinase 14 inhibitor isoxazole 80 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00332269 CHEMBL1257304 Bioactive AGN-PC-09M6OZ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26833 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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